Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | SQLE | Q14534 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230713 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL7776391 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL709979 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL4780329 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL1905061 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL2229412 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL73977 | 0.98 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL158028 | 0.98 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL5092302 | 0.98 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL6924137 | 0.96 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113186183-B | Difunctional sesterterpene/diterpene synthase LcTPS2, coding gene, product and application thereof | 中国科学院昆明植物研究所 | 2023-05-16 | — | — | CN | disclosed |
| CN-113186183-A | Difunctional sesterterpene/diterpene synthase LcTPS2, coding gene and product and application thereof | 中国科学院昆明植物研究所 | 2021-07-30 | — | — | CN | disclosed |
| CN-108239631-B | Terpene synthase and application thereof | 武汉臻智生物科技有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-104673813-B | A kind of ophiobolin class compound parent nucleus synthetic gene AuOS and its application | 武汉大学 | 2017-07-28 | — | — | CN | disclosed |
| CN-103857689-A | OSW-1 analogs and conjugates, and uses thereof | HARVARD COLLEGE | 2014-06-11 | — | — | CN | disclosed |
| CN-103667370-A | Polynucleotides encoding isoprenoid modifying enzymes and methods of use thereof | UNIV CALIFORNIA | 2014-03-26 | — | — | CN | disclosed |
| CN-101495499-B | Polynucleotides encoding isoprenoid-modifying enzymes and methods of use thereof | UNIV CALIFORNIA | 2013-09-04 | — | — | CN | disclosed |
| US-8450560-B2 | Gene cluster of prenyl transferase from Hevea brasiliensis | BRIDGESTONE CORPORATION (JP) | 2013-05-28 | — | — | US | disclosed |
| US-20100186111-A1 | GENE CLUSTER OF PRENYL TRANSFERASE FROM HEVEA BRASILIENSIS | BRIDGESTONE CORPORATION (JP) | 2010-07-22 | — | — | US | disclosed |
| US-7692066-B2 | Gene cluster of prenyl transferase from Hevea brasiliensis | BRIDGESTONE CORPORATION (JP) | 2010-04-06 | — | — | US | disclosed |
| CN-101495499-A | Polynucleotides encoding isoprenoid-modifying enzymes and methods of use thereof | UNIV CALIFORNIA (US) | 2009-07-29 | — | — | CN | disclosed |
| CN-101283089-A | Nucleic acids encoding modified cytochrome P450 enzymes and methods of use thereof | UNIV CALIFORNIA (US) | 2008-10-08 | — | — | CN | disclosed |
| CN-101023181-A | Method for enhancing production of isoprenoid compounds | UNIV CALIFORNIA (US) | 2007-08-22 | — | — | CN | disclosed |
| CN-101001947-A | Genetically modified host cells and use of same for producing isoprenoid compounds | UNIV CALIFORNIA (US) | 2007-07-18 | — | — | CN | disclosed |
| US-20070067866-A1 | Gene cluster of prenyl transferase from Hevea brasiliensis | BRIDGESTONE CORPORATION | 2007-03-22 | — | — | US | disclosed |