Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.57 |
| ▸ | SQLE | Q14534 | 7/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230713 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL3273420 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL709979 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL4780329 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL1905061 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL2229412 | 1.00 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL73977 | 0.98 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL158028 | 0.98 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL5092302 | 0.98 | KMT2A (0.60) | KMT2AMAPTALDH1A1MEN1CYP3A4 | |
| SCHEMBL6924137 | 0.96 | KMT2A (0.64) | KMT2AMAPTALDH1A1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781552-B1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO (JP) | 2001-07-25 | — | — | EP | disclosed |
| US-6011069-A | N-POLYISOPRENYL-N,N'-DIBENZYLETHYLENEDIAMINES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 2000-01-04 | — | — | US | disclosed |
| EP-0787716-B1 | Isoprene derivatives | NISSHIN FLOUR MILLING CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| US-5756475-A | POLYISOPRENE MODIFIED WITH AMINE WITH ANTICANCER AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0787716-A1 | Isoprene derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-08-06 | — | — | EP | disclosed |
| EP-0781552-A1 | Multidrug resistance inhibitors | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-07-02 | — | — | EP | disclosed |