SCHEMBL4780329

SCHEMBL4780329

CC(C)=CCCC(C)=CCCC(C)=CC[CH]/C=C(\C)CCC=C(C)C

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.64
MAPT P10636 2/20 0.57
ALDH1A1 P00352 2/20 0.57
MEN1 O00255 2/20 0.57
CYP3A4 P08684 2/20 0.57
ALOX15 P16050 2/20 0.57
UGT1A1 P22309 1/20 0.57
SQLE Q14534 7/20 0.55
KDM4E B2RXH2 1/20 0.52
NR1I2 O75469 1/20 0.48
LMNA P02545 1/20 0.48
PGR P06401 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2230713 1.00 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL3273420 1.00 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL7776391 1.00 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL709979 1.00 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL1905061 1.00 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL2229412 1.00 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL73977 0.98 KMT2A (0.60) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL158028 0.98 KMT2A (0.60) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL5092302 0.98 KMT2A (0.60) KMT2AMAPTALDH1A1MEN1CYP3A4
SCHEMBL6924137 0.96 KMT2A (0.64) KMT2AMAPTALDH1A1MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023212400-A1 FERMENTATION PROCESSES AND SYSTEMS MANUS BIO INC. (US) 2023-11-02 WO claimed
EP-3337893-B1 INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES MANUS BIO INC (US) 2023-07-19 EP claimed
US-20230180691-A1 SECONDARY METABOLITE SCREENING SYSTEM MANUS BIO INC. 2023-06-15 US claimed
US-20210161092-A1 SECONDARY METABOLITE SCREENING SYSTEM MANUS BIO INC. 2021-06-03 US claimed
US-20200377865-A1 INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES MANUS BIO INC. 2020-12-03 US claimed
US-10774314-B2 Increasing productivity of E. coli host cells that functionally express P450 enzymes MANUS BIO INC. (US) 2020-09-15 US claimed
US-20180251738-A1 INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES SYMBIOTIC CAPITAL AGENCY LLC, AS ADMINISTRATIVE AND COLLATERAL AGENT 2018-09-06 US claimed
EP-3337893-A1 INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES Manus Biosynthesis, Inc. (US) 2018-06-27 EP claimed
WO-2017142993-A1 SECONDARY METABOLITE SCREENING SYSTEM MANUS BIOSYNTHESIS, INC. (US) 2017-08-24 WO claimed
WO-2017034942-A1 INCREASING PRODUCTIVITY OF E. COLI HOST CELLS THAT FUNCTIONALLY EXPRESS P450 ENZYMES MANUS BIOSYNTHESIS, INC. (US) 2017-03-02 WO claimed
US-20240199704-A1 GENETICALLY ENCODED SYSTEM FOR CONSTRUCTING AND DETECTING BIOLOGICALLY ACTIVE AGENTS THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE 2024-06-20 US disclosed
US-11993635-B2 Genetically encoded system for constructing and detecting biologically active agents THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2024-05-28 US disclosed
EP-4266058-A9 GENETICALLY ENCODED SYSTEM FOR CONSTRUCTING AND DETECTING BIOLOGICALLY ACTIVE AGENTS The Regents of the University of Colorado, a body corporate (US) 2023-12-13 EP disclosed
EP-3818153-B1 GENETICALLY ENCODED SYSTEM FOR CONSTRUCTING AND DETECTING BIOLOGICALLY ACTIVE AGENTS UNIV COLORADO REGENTS (US) 2023-12-13 EP disclosed
EP-4266058-A2 GENETICALLY ENCODED SYSTEM FOR CONSTRUCTING AND DETECTING BIOLOGICALLY ACTIVE AGENTS The Regents of the University of Colorado, a body corporate (US) 2023-10-25 EP disclosed
CN-102933666-A Binders for self-polishing antifouling coatings PPG COATINGS EUROP B V 2013-02-13 CN disclosed
CN-102884142-A Coating composition PPG COATINGS EUROP B V 2013-01-16 CN disclosed
CN-102812129-A Microbial Engineering For The Production Of Chemical And Pharmaceutical Products From The Isoprenoid Pathway MASSACHUSETTS INST TECHNOLOGY 2012-12-05 CN disclosed
WO-2008021367-A2 MOENOMYCIN BIOSYNTHESIS-RELATED COMPOSITIONS AND METHODS OF USE THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2008-02-21 WO disclosed
US-6020177-A Heptaprenyl diphosphate-synthetase TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2000-02-01 US disclosed