SCHEMBL73977

SCHEMBL73977

CC(C)=CCC/C(C)=C/[CH]C/C=C(\C)CCC=C(C)C

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
ALDH1A1 P00352 3/20 0.57
ALOX15 P16050 3/20 0.56
MEN1 O00255 2/20 0.56
CYP3A4 P08684 2/20 0.56
MAPT P10636 2/20 0.54
UGT1A1 P22309 1/20 0.54
SQLE Q14534 7/20 0.52
NR1I2 O75469 1/20 0.50
LMNA P02545 1/20 0.50
PGR P06401 1/20 0.50
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5092302 1.00 KMT2A (0.60) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL158028 1.00 KMT2A (0.60) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL3273420 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL4780329 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL2230713 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL2229412 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL1905061 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL7776391 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL709979 0.98 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4
SCHEMBL6924137 0.94 KMT2A (0.64) KMT2AALDH1A1ALOX15MEN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8171 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240240160-A1 NOVEL OLIVETOL SYNTHASES FOR CANNABINOID PRODUCTION CREO INGREDIENTS, INC. 2024-07-18 US claimed
CN-118339307-A Biosynthetic preparation of vitamin A compounds 康纳根有限公司 2024-07-12 CN claimed
CN-118240859-A Candida tropicalis engineering bacteria for producing squalene and construction method thereof 江南大学 2024-06-25 CN claimed
CN-117965334-B Recombinant pichia pastoris strain for expressing astaxanthin as well as construction method and application thereof 中国农业科学院生物技术研究所 2024-06-25 CN claimed
CN-118240674-A Recombinant pichia pastoris for producing retinol, construction method and application thereof 南京工业大学 2024-06-25 CN claimed
CN-114686452-B Artificial protein skeleton and application thereof 中国科学院深圳先进技术研究院 2024-06-18 CN claimed
CN-118146970-A Recombinant pichia pastoris for producing astaxanthin as well as construction method and application thereof 南京工业大学 2024-06-07 CN claimed
US-20240180932-A1 SUBSTITUTED RESORCYLIC ACID COMPOUNDS IN THE MANAGEMENT OF AGEING AND RELATED DISORDERS NESTLE SA (CH) 2024-06-06 US claimed
US-20240174987-A1 UDP-DEPENDENT GLYCOSYLTRANSFERASE FOR HIGH EFFICIENCY PRODUCTION OF REBAUDIOSIDES CORN PRODUCTS DEVELOPMENT, INC. 2024-05-30 US claimed
CN-118028199-A Recombinant escherichia coli for high-yield cembratrienol, construction method and application 郑州轻工业大学 2024-05-14 CN claimed
WO-1995020396-A1 INHIBITORS OF GERANYLGERANYL-PROTEIN TRANSFERASE MERCK & CO., INC. (US) 1995-08-03 WO claimed
WO-1995013059-A1 FARNESYL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) 1995-05-18 WO claimed
WO-1994001126-A1 COMPOUNDS FOR INHIBITION OF PROTEOLYSIS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1994-01-20 WO claimed
EP-0471056-A4 1994-01-12 EP claimed
EP-0540782-A1 Use of analogues of polyisoprenyl pyrophosphate for inhibiting protein isoprenylation NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) 1993-05-12 EP claimed
US-5202456-A Anticarcinogenic agents; methylating transferase inhibitors; farnesyl or geranyl sulfur-, oxygen or selenium-containing derivatives THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1993-04-13 US claimed
WO-1992018465-A2 COMPOUNDS FOR INHIBITION OF PROTEIN METHYLATION THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1992-10-29 WO claimed
EP-0471056-A1 BIOSYNTHESIS OF CAROTENOIDS IN GENETICALLY ENGINEERED HOSTS AMOCO CORPORATION (US) 1992-02-19 EP claimed
WO-1991013078-A1 BIOSYNTHESIS OF CAROTENOIDS IN GENETICALLY ENGINEERED HOSTS AMOCO CORPORATION (US) 1991-09-05 WO claimed
US-4229356-A Production of vitamin K1 and vitamin K2 WAKUNAGA YAKUHIN KABUSHIKI KAISHA (JP) 1980-10-21 US claimed