Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.54 |
| ▸ | SQLE | Q14534 | 7/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73977 | 1.00 | KMT2A (0.60) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL158028 | 1.00 | KMT2A (0.60) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL3273420 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL4780329 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL2230713 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL2229412 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL1905061 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL7776391 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL709979 | 0.98 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 | |
| SCHEMBL6924137 | 0.94 | KMT2A (0.64) | KMT2AALDH1A1ALOX15MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348017-B2 | Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin | SHISEIDO CO., LTD. (JP) | 2008-03-25 | — | — | US | disclosed |
| US-20040236111-A1 | Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin | SHISEIDO CO., LTD. (JP) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236111-A1 | Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin | MMP1, MMP2, MMP3 | KMT2A 2099/4885ALDH1A1 253/4885ALOX15 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.