Sugi Predict

Sugi Predict / Compounds / SCHEMBL826022

SCHEMBL826022

SCHEMBL826022

N=c1cc2oc3cc(N)ccc3nc-2c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 11/20 0.45
▸ MEN1 O00255 9/20 0.45
▸ RAB9A P51151 9/20 0.45
▸ NPC1 O15118 8/20 0.45
▸ POLB P06746 2/20 0.45
▸ MAPT P10636 10/20 0.44
▸ ALDH1A1 P00352 7/20 0.44
▸ KDM4E B2RXH2 7/20 0.44
▸ SMN1; SMN2 Q16637 7/20 0.44
▸ HPGD P15428 6/20 0.44
▸ GLA P06280 1/20 0.44
▸ GAA P10253 1/20 0.44
▸ ATM Q13315 2/20 0.40
▸ TLR9 Q9NR96 1/20 0.40
▸ HSD17B10 Q99714 3/20 0.38
▸ PTPRA P18433 1/20 0.37
▸ PTPRB P23467 1/20 0.37
▸ TP53 P04637 4/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ PKM P14618 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Perchlorate SCHEMBL29361888 0.92 KMT2A (0.41) KMT2AMEN1RAB9ANPC1POLB
Acetic Acid SCHEMBL313911 0.91 KMT2A (0.45) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL3275224 0.84 KMT2A (0.62) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL12364543 0.81 NPC1 (0.45) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL22901136 0.78 MEN1 (0.44) KMT2AMEN1RAB9ANPC1POLB
Nile Blue SCHEMBL29356294 0.77 MEN1 (0.77) KMT2AMEN1RAB9ANPC1POLB
Nile Blue SCHEMBL12393690 0.77 MEN1 (0.77) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL14234593 0.76 MAPT (0.50) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL10327168 0.75 PTPRA (0.50) KMT2AMEN1RAB9ANPC1POLB
Alanine SCHEMBL3274115 0.75 PTPRA (0.58) KMT2AMEN1RAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090029480-A1 Testing device VERITEQUE USA, INC. 2009-01-29 — — US claimed
EP-1844321-A1 TESTING DEVICE System Two Pty Ltd (AU) 2007-10-17 — — EP claimed
WO-2006079167-A1 TESTING DEVICE SYSTEM TWO PTY LTD (AU) 2006-08-03 — — WO claimed
US-10976258-B2 Porous planar cell capture system and method of use CHARLES RIVER LABORATORIES, INC. (US) 2021-04-13 — — US disclosed
US-20210063411-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MED SYST INC (US) 2021-03-04 — — US disclosed
US-10883999-B2 Detecting targets using mass tags and mass spectrometry VENTANA MEDICAL SYSTEMS, INC. (US) 2021-01-05 — — US disclosed
US-20200174008-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS WATERS TECHNOLOGIES CORPORATION 2020-06-04 — — US disclosed
US-10436790-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2019-10-08 — — US disclosed
US-10416166-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals WATERS TECHNOLOGIES CORPORATION (US) 2019-09-17 — — US disclosed
US-20190187056-A1 POROUS PLANAR CELL CAPTURE SYSTEM JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2019-06-20 — — US disclosed
US-10324036-B2 Porous planar cell capture system CHARLES RIVER LABORATORIES, INC. (US) 2019-06-18 — — US disclosed
EP-1953239-A1 METHOD FOR DETERMINATION OF ALLERGEN IN ENVIRONMENT AND KIT FOR SIMPLE QUANTIFICATION OF ALLERGEN Japan Science and Technology Agency (JP) 2008-08-06 — — EP disclosed
WO-2008087031-A1 POLYMERIC ANIONS/CATIONS MERCK PATENT GMBH (DE) 2008-07-24 — — WO disclosed
US-20070290195-A1 Increased open-circuit-voltage organic photosensitive devices ENERGY, UNITED STATES DEPARTMENT OF 2007-12-20 — — US disclosed
US-20070290195-A1 Increased open-circuit-voltage organic photosensitive devices ENERGY, UNITED STATES DEPARTMENT OF 2007-12-20 — — US disclosed
US-20070155022-A1 Degenerate binding detection and protein identification using Raman spectroscopy nanoparticle labels INTEL CORPORATION 2007-07-05 — — US disclosed
US-20070155022-A1 Degenerate binding detection and protein identification using Raman spectroscopy nanoparticle labels INTEL CORPORATION 2007-07-05 — — US disclosed
US-7238789-B2 Sulfonated [8,9] benzophenoxazine dyes and the use of their labelled conjugates APPLERA CORPORATION (US) 2007-07-03 — — US disclosed
US-20070048797-A1 Composite organic inorganic nanoclusters as carriers and identifiers of tester molecules SU XING 2007-03-01 — — US disclosed
US-20070048797-A1 Composite organic inorganic nanoclusters as carriers and identifiers of tester molecules SU XING 2007-03-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10416166-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals FUT5, FUT6, CSGALNACT1 KMT2A 2567/4885MEN1 1968/4885RAB9A 981/4885
US-20200174008-A1 RAPID FLUORESCENCE TAGGING OF GLYCANS AND OTHER BIOMOLECULES WITH ENHANCED MS SIGNALS FUT5, FUT6, CSGALNACT1 KMT2A 3081/4885MEN1 2746/4885RAB9A 1001/4885
US-10436790-B2 Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals FUT5, FUT6, CSGALNACT1 KMT2A 2419/4885MEN1 2175/4885RAB9A 551/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.