Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL125553 | 0.99 | CASP3 (0.56) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL3274206 | 0.88 | MEN1 (0.57) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL22901136 | 0.82 | MEN1 (0.44) | CASP3SENP8SENP7SENP6NPC1 | |
| Acetic Acid SCHEMBL313911 | 0.80 | KMT2A (0.45) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL3275818 | 0.75 | MEN1 (0.53) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL826022 | 0.75 | KMT2A (0.45) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL14347198 | 0.73 | RAB9A (0.62) | CASP3SENP8SENP7SENP6NPC1 | |
| SCHEMBL28432579 | 0.73 | MEN1 (0.55) | NPC1RAB9AKMT2AMEN1KDM4E | |
| SCHEMBL17153952 | 0.72 | NPC1 (0.66) | CASP3SENP8SENP7SENP6NPC1 | |
| Perchlorate SCHEMBL29361888 | 0.71 | KMT2A (0.41) | NPC1RAB9AKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969339-B2 | Compositions and methods for bone formation and modeling | ENZO BIOCHEM, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | ENZO BIOCHEM, INC. (US) | 2013-07-04 | — | — | US | disclosed |
| US-8367822-B2 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367822-B2 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120178747-A9 | Compositions and methods for bone formation and remodeling | ENZO LIFE SCIENCES, INC. | 2012-07-12 | — | — | US | disclosed |
| US-20100298308-A1 | Compositions and methods for bone formation and remodeling | ENZO THERAPEUTICS, INC. | 2010-11-25 | — | — | US | disclosed |
| US-20090311484-A1 | Molecular Resist Compositions, Methods of Patterning Substrates Using the Compositions and Process Products Prepared Therefrom | NANO TERRA INC. (US) | 2009-12-17 | — | — | US | disclosed |
| US-20090311484-A1 | Molecular Resist Compositions, Methods of Patterning Substrates Using the Compositions and Process Products Prepared Therefrom | NANO TERRA INC. (US) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172332-A1 | COMPOSITIONS AND METHODS FOR BONE FORMATION AND MODELING | LRP6, BMP6, WNT3A | CASP3 1948/4885SENP8 1560/4885SENP7 1929/4885 |
| US-20100298308-A1 | Compositions and methods for bone formation and remodeling | DKK1, BMP6, LRP6 | CASP3 3941/4885SENP8 2749/4885SENP7 1935/4885 |
| US-20120178747-A9 | Compositions and methods for bone formation and remodeling | DKK1, BMP6, LRP6 | CASP3 3941/4885SENP8 2749/4885SENP7 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.