Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | RPS6KA2 | Q15349 | 2/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15461382 | 0.85 | MAPK14 (0.48) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL24783813 | 0.82 | ALDH1A1 (0.55) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL16254888 | 0.79 | MAPK14 (0.52) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL1011745 | 0.78 | MAPK14 (0.46) | MAPK14IDO1RAB9APDE10AALDH1A1 | |
| SCHEMBL16254942 | 0.78 | MAPK14 (0.51) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL13391769 | 0.76 | MAPK14 (0.44) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL16253026 | 0.75 | MAPK14 (0.49) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL26790004 | 0.75 | MAPK14 (0.52) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL26991154 | 0.74 | MAPK14 (0.40) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 | |
| SCHEMBL31148185 | 0.74 | CNR2 (0.46) | MAPK14CNR2IDO1RPS6KA2RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-16 | — | — | US | disclosed |
| EP-2199282-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2010-06-23 | — | — | EP | disclosed |
| US-20090163508-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234389-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | MAPK14 2825/4885CNR2 7/4885IDO1 841/4885 |
| US-20090163508-A1 | AMIDE COMPOUND | FAAH, FAAH2, NAAA | MAPK14 2825/4885CNR2 7/4885IDO1 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.