Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.73 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.73 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.73 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.73 |
| ▸ | DRD3 | P35462 | 1/20 | 0.73 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.53 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.53 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.53 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | AR | P10275 | 5/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3275082 | 1.00 | PGR (0.73) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| SCHEMBL11699972 | 0.87 | PGR (0.80) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| SCHEMBL22382736 | 0.87 | PGR (0.76) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norgestimate SCHEMBL15233395 | 0.84 | PGR (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norgestimate SCHEMBL38317 | 0.84 | PGR (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norgestimate SCHEMBL5173707 | 0.84 | PGR (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norgestimate SCHEMBL633395 | 0.84 | PGR (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norgestimate SCHEMBL38318 | 0.84 | PGR (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norelgestromin SCHEMBL3267125 | 0.81 | NR1I2 (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 | |
| Norelgestromin SCHEMBL4814600 | 0.81 | NR1I2 (1.00) | PGRSLC6A4NR3C1NR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641812-B1 | PURE d-(17alpha)-13-ETHYL-17-HYDROXY-18,19-DINORPREGN-4-ENE-20-YNE-3-ONE-3E- AND -3Z-OXIME ISOMERS, AS WELL AS PROCESS FOR THE SYNTHESIS OF THE MIXTURE OF ISOMERS AND THE PURE ISOMERS | RICHTER GEDEON NYRT (HU) | 2010-06-09 | — | — | EP | disclosed |
| EP-1641812-A1 | PURE D-(17a)-13-ETHYL-17-HYDROXY-18,19-DINORPREGN-4-ENE-20-YNE-3-ONE-3E- AND -3Z-OXIME ISOMERS, AS WELL AS PROCESS FOR THE SYNTHESIS OF THE MIXTURE OF ISOMERS AND THE PURE ISOMERS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2006-04-05 | — | — | EP | disclosed |
| WO-2005000867-A1 | PURE D-(17α)-13-ETHYL-17-HYDROXY-18,19-DINORPREGN-4-ENE-20-YNE-3-ONE-3E- AND -3Z-OXIME ISOMERS, AS WELL AS PROCESS FOR THE SYNTHESIS OF THE MIXTURE OF ISOMERS AND THE PURE ISOMERS | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2005-01-06 | — | — | WO | disclosed |