Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 12/20 | 0.46 |
| ▸ | GABRP | O00591 | 2/20 | 0.42 |
| ▸ | GABRD | O14764 | 2/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.42 |
| ▸ | GABRE | P78334 | 2/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3273833 | 1.00 | MME (0.47) | MMEFOLH1GABRPGABRDGABRA1 | |
| SCHEMBL1419634 | 1.00 | MME (0.47) | MMEFOLH1GABRPGABRDGABRA1 | |
| SCHEMBL3931367 | 0.86 | GABRP (0.43) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11414780 | 0.85 | CYP1A2 (0.44) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1419611 | 0.85 | SLC1A1 (0.50) | MMEFOLH1CA1CA2 | |
| SCHEMBL994043 | 0.83 | FOLH1 (0.41) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2979680 | 0.81 | MME (0.53) | MMEFOLH1CA1CA2 | |
| SCHEMBL16350134 | 0.80 | FOLH1 (0.39) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL764175 | 0.80 | FOLH1 (0.39) | FOLH1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1177029 | 0.80 | MME (0.58) | MMECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087525-A1 | STEREOSELECTIVE ENZYMATIC SYNTHESIS OF (S) OR (R)-ISO-BUTYL-GLUTARIC ESTER | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2010-04-08 | — | — | US | disclosed |
| WO-2009158343-A1 | STEREOSELECTIVE ENZYMATIC SYNTHESIS OF (S) OR (R)-ISO-BUTYL-GLUTARIC ESTER | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087525-A1 | STEREOSELECTIVE ENZYMATIC SYNTHESIS OF (S) OR (R)-ISO-BUTYL-GLUTARIC ESTER | COASY, HSD17B12, GABRB2 | MME 851/4885FOLH1 718/4885GABRP 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.