Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CRHBP | P24387 | 1/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30352851 | 1.00 | TDP1 (0.66) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL2816974 | 0.94 | CRHBP (0.61) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL14366620 | 0.92 | TDP1 (0.56) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL14001771 | 0.92 | TDP1 (0.56) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL28122064 | 0.92 | ALDH1A1 (0.56) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL15791110 | 0.90 | TDP1 (0.53) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL14002370 | 0.87 | TDP1 (0.51) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL24757925 | 0.86 | ALDH1A1 (0.58) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL17742439 | 0.85 | TDP1 (0.66) | TDP1ALDH1A1CRHBPCRHR2MAPT | |
| SCHEMBL2958562 | 0.84 | ALDH1A1 (0.92) | TDP1ALDH1A1CRHBPCRHR2HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039849-B | Preparation method of carbazole ring-containing compound | 阜阳欣奕华材料科技有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-111039849-A | Preparation method of carbazole ring-containing compound | 阜阳欣奕华材料科技有限公司 | 2020-04-21 | — | — | CN | disclosed |
| CN-104851977-B | Organic energetic chip and method for preparing same by using silicon wafer as substrate | 南京理工大学 | 2017-06-27 | — | — | CN | disclosed |
| CN-105061296-A | Preparation method for 2-substituted carbazole compounds | ZHANGJIAGANG IND TECHNOLOGY RES INST JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY | 2015-11-18 | — | — | CN | disclosed |
| US-8343637-B2 | Carbazole derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2013-01-01 | — | — | US | disclosed |
| EP-2102309-B1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2010-06-30 | — | — | EP | disclosed |
| CN-101133016-B | Method for producing substituted biphenyls | BASF AG | 2010-06-02 | — | — | CN | disclosed |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| CN-101600777-A | The type material that is used for organic electroluminescence device | MERCK PATENT GMBH (DE) | 2009-12-09 | — | — | CN | disclosed |
| EP-2102309-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | Merck Patent GmbH (DE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008086851-A1 | CARBAZOLE DERIVATIVES FOR ORGANC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2008-07-24 | — | — | WO | disclosed |
| CN-101133016-A | Method for producing substituted biphenyls | BASF AG (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABBOTT LABORATORIES | 2006-04-06 | — | — | US | disclosed |
| CN-1163452-C | Process for preparing nitrobiphenylene | �����ɷ� | 2004-08-25 | — | — | CN | disclosed |
| CN-1213359-A | Process for preparing nitrobiphenylene | BASF AG (DE) | 1999-04-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074102-A1 | Kinase inhibitors as therapeutic agents | ABL1, MAP3K19, MAP3K20 | TDP1 1395/4885ALDH1A1 2415/4885CRHBP 4743/4885 |
| US-20090302752-A1 | CARBAZOLE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | PIEZO1, CACNA2D1, CYCS | TDP1 1018/4885ALDH1A1 208/4885CRHBP 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.