Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3276914 | 0.86 | ALDH1A1 (0.41) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL4456102 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL27888110 | 0.79 | MLYCD (0.45) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL7405520 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL10861618 | 0.79 | MLYCD (0.45) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL7405523 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL7209762 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL7537102 | 0.75 | SMPD2 (0.39) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL3276902 | 0.75 | SMPD2 (0.39) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 | |
| SCHEMBL21776703 | 0.74 | NPSR1 (0.41) | ALDH1A1LMNATP53SMN1; SMN2SMPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951943-B2 | Method for preparing and purifying 3-hydroxyamidinophenylalanine compounds | WILEX AG (DE) | 2011-05-31 | — | — | US | disclosed |
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2009-04-16 | — | — | US | disclosed |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | WILEX AG (DE) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099360-A9 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | PEPD, PAH, PRSS3 | ALDH1A1 2416/4885LMNA 1222/4885TP53 4132/4885 |
| US-20080039626-A1 | Method for Cleaning 3-Hydroxyamidinophenylalanine Derivatives by the Precepitation and Recrystallization of Salt and an Aromatic Sulfonic Acid | PEPD, PAH, PRSS3 | ALDH1A1 2416/4885LMNA 1222/4885TP53 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.