Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | RBP4 | P02753 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3279027 | 0.92 | ACHE (0.33) | NPSR1CES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3278391 | 0.91 | ACHE (0.32) | NPSR1CES2 | |
| Hydrochloric Acid SCHEMBL3277978 | 0.90 | MEN1 (0.32) | NPSR1GAAMEN1KMT2ATP53 | |
| Hydrochloric Acid SCHEMBL3284366 | 0.89 | ALDH1A1 (0.32) | NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3278866 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL2276943 | 0.87 | GAA (0.33) | NPSR1GAACES2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3270199 | 0.87 | CYP2B6 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1236180 | 0.85 | MEN1 (0.33) | GAACES2MEN1KMT2AATM | |
| Hydrochloric Acid SCHEMBL3277752 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1235713 | 0.83 | TAS1R3 (0.34) | GAACES2MEN1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1803742-B1 | PROCESS FOR PRODUCING PROPYLENE POLYMER | MITSUI CHEMICALS INC (JP) | 2010-06-23 | — | — | EP | disclosed |