Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | TYMP | P19971 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30424976 | 0.80 | CYP2A6 (0.54) | CYP2A6CYP1A2TYMPRORCRORB | |
| SCHEMBL7637791 | 0.79 | CYP1A2 (0.52) | CYP2A6CYP1A2TYMPRORCRORB | |
| SCHEMBL24758930 | 0.79 | CYP2A6 (0.52) | CYP2A6CYP1A2TYMPRORCRORB | |
| SCHEMBL367587 | 0.78 | DNMT1 (0.47) | CYP2A6CYP1A2TYMPDHFRKDM4E | |
| SCHEMBL30944688 | 0.78 | DNMT1 (0.47) | CYP2A6CYP1A2TYMPDHFRKDM4E | |
| SCHEMBL365419 | 0.77 | ALDH1A1 (0.43) | CYP2A6CYP1A2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL30866412 | 0.77 | CYP2A6 (0.65) | CYP2A6CYP1A2TYMPRORCRORB | |
| SCHEMBL9770068 | 0.77 | CYP2A6 (0.65) | CYP2A6CYP1A2TYMPRORCRORB | |
| SCHEMBL6035360 | 0.77 | CYP1A2 (0.44) | CYP2A6CYP1A2TYMPRORCRORB | |
| SCHEMBL4268573 | 0.77 | CYP2A6 (0.48) | CYP2A6CYP1A2TYMPRORCRORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7696349-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2010-04-13 | — | — | US | disclosed |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | BASF AKTIENGESELLSCHAFT (DE) | 2009-12-31 | — | — | US | disclosed |
| US-7442842-B2 | Method for asymmetric synthesis | BASF SE (DE) | 2008-10-28 | — | — | US | disclosed |
| US-20070073092-A1 | Method for asymmetric synthesis | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073092-A1 | Method for asymmetric synthesis | COASY, PIN1, INF2 | CYP2A6 31/4885CYP1A2 127/4885TYMP 1016/4885 |
| US-20090326226-A1 | METHOD FOR ASYMMETRIC SYNTHESIS | COASY, PIN1, INF2 | CYP2A6 31/4885CYP1A2 127/4885TYMP 1016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.