SCHEMBL367587

SCHEMBL367587

Pc1ccc2ccccc2c1-c1cccc2ccccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.47
ALDH1A1 P00352 6/20 0.46
HSD17B10 Q99714 4/20 0.46
CYP2A6 P11509 2/20 0.46
TSHR P16473 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
DHFR P00374 1/20 0.43
HPRT1 P00492 1/20 0.42
TYMP P19971 1/20 0.42
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
WDR5 P61964 1/20 0.39
CYP1A2 P05177 2/20 0.39
HPGD P15428 2/20 0.39
HIF1A Q16665 1/20 0.39
CYP1B1 Q16678 1/20 0.39
THRB P10828 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30944688 1.00 DNMT1 (0.47) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL5417907 0.84 ALDH1A1 (0.58) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL1820374 0.80 DHFR (0.42) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL196007 0.80 DNMT1 (0.59) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29410608 0.80 DNMT1 (0.59) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29787010 0.80 DNMT1 (0.59) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL29407412 0.79 ALDH1A1 (0.50) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL702934 0.79 ALDH1A1 (0.50) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL31307687 0.78 DNMT1 (0.57) DNMT1ALDH1A1HSD17B10CYP2A6TSHR
SCHEMBL30122801 0.78 DNMT1 (0.47) DNMT1ALDH1A1HSD17B10CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340572-A Diphosphine ligand containing xanthene skeleton and synthesis and application thereof 南方科技大学 2022-11-15 CN claimed
CN-112876376-B Synthesis method of allyl aryl compound 山东领海生物科技有限公司 2022-11-01 CN claimed
CN-114685408-A Preparation method of alkyl furan compound 华南理工大学 2022-07-01 CN claimed
CN-112876376-A Synthesis method of allyl aryl compound 山东领海生物科技有限公司 2021-06-01 CN claimed
EP-0771812-A1 Method for producing an optically active diphosphine Takasago International Corporation (JP) 1997-05-07 EP claimed
EP-0544455-B1 Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO PERFUMERY CO LTD (JP) 1997-02-12 EP claimed
EP-0444930-B1 Compounds containing 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl and catalytic metal complexes thereof TAKASAGO PERFUMERY CO LTD (JP) 1994-11-30 EP claimed
US-5324861-A Selective hydrogenation of olefins, ketones, imines TAKASAGO INTERNATIONAL CORPORATION (JP) 1994-06-28 US claimed
US-5274146-A Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-12-28 US claimed
EP-0544455-A1 Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-06-02 EP claimed
CN-122080424-A Tetraphenyl ethylene chiral metal cage complex based on chiral Pt metal coordination and preparation method and application thereof 2026-05-26 CN disclosed
US-20250100972-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOZONANT AND/OR DYE CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2025-03-27 US disclosed
EP-4373677-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOZONANT AND/OR DYE Continental Reifen Deutschland GmbH (DE) 2024-05-29 EP disclosed
CN-117693430-A Compound, rubber blend comprising the compound, vehicle tyre comprising the rubber blend in at least one component, method for producing the compound and use of the compound as an ageing protectant and/or antiozonant and/or dye 大陆轮胎德国有限公司 2024-03-12 CN disclosed
CN-116947925-A Bridged biphenyl monophosphine ligand containing benzofuran structure, and preparation method and application thereof 中山大学 2023-10-27 CN disclosed
US-5274146-A Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-12-28 US disclosed
US-5274146-A Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-12-28 US disclosed
EP-0544455-A1 Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-06-02 EP disclosed
EP-0544455-A1 Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-06-02 EP disclosed
EP-0544455-A1 Water-soluble alkali metal sulfonate-substituted binaphthylphosphine transition metal complex and enantioselective hydrogenation method using it TAKASAGO INTERNATIONAL CORPORATION (JP) 1993-06-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250100972-A1 COMPOUND, RUBBER BLEND CONTAINING THE COMPOUND, VEHICLE TIRE COMPRISING THE RUBBER BLEND IN AT LEAST ONE COMPONENT, PROCESS FOR PRODUCING THE COMPOUND, AND USE OF THE COMPOUND AS AN AGEING PROTECTANT AND/OR ANTIOZONANT AND/OR DYE TERT, POT1, RIF1 DNMT1 2652/4885ALDH1A1 2119/4885HSD17B10 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.