Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5199972 | 0.88 | FKBP1A (0.30) | FKBP1A | |
| SCHEMBL6840778 | 0.74 | TSHR (0.40) | ALDH1A1FKBP1ATSHRPOLB | |
| SCHEMBL2517427 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HPGDATMKMT2AMAPT | |
| SCHEMBL30229409 | 0.72 | KDM4E (0.44) | ALDH1A1HPGDKDM4EHSD17B10KMT2A | |
| SCHEMBL1093243 | 0.72 | CA1 (0.39) | ALDH1A1HPGDKDM4EHSD17B10FKBP1A | |
| SCHEMBL2987389 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HPGDATMKMT2AMAPT | |
| SCHEMBL22273668 | 0.71 | FKBP1A (0.33) | FKBP1A | |
| SCHEMBL23640661 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10ATM | |
| SCHEMBL16516708 | 0.71 | ALDH1A1 (0.40) | ALDH1A1HPGDKDM4EHSD17B10FKBP1A | |
| SCHEMBL291084 | 0.70 | FKBP1A (0.39) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7855242-B2 | Dental resin composition, method of manufacture, and method of use thereof | PENTRON CLINICAL TECHNOLOGIES LLC (US) | 2010-12-21 | — | — | US | claimed |
| US-20070049656-A1 | DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | PENTRON CLINICAL TECHNOLOGIES, INC (US) | 2007-03-01 | — | — | US | claimed |
| US-20040249015-A1 | Method of manufacturing dental restorations | KERR CORPORATION | 2004-12-09 | — | — | US | claimed |
| US-6787584-B2 | BIODEGRADABLE MACROMONOMER HAVING TERMINAL ACRYLATE OR METHACRYLATE GROUP(S) (ACRYLATED POLYLACTONE); A CURING COMPOSITION; A FILLER OF BIOACTIVE GLASS, APATITES, AND OTHER (METH)ACRYLATES | PENTRON CORPORATION | 2004-09-07 | — | — | US | claimed |
| WO-2002078646-A1 | DENTAL COMPOSITIONS | PENTRON CORPORATION (US) | 2002-10-10 | — | — | WO | claimed |
| US-6455608-B1 | CURABLE DENTAL FORMULATION COMPRISING DEGRADABLE MACROMONOMERS HAVING ONE OR MORE TERMINAL ACRYLATE OR METHACRYLATE FUNCTIONALITY, A CURING AGENT; PREPARING A SITE TO BE RESTORED IN A TOOTH AND APPLYING ABOVE FORMULATION | JENERIC/PENTRON INCORPORATED | 2002-09-24 | — | — | US | claimed |
| US-20020120033-A1 | Biodegradable macromonomer having terminal acrylate or methacrylate group(s) (acrylated polylactone); a curing composition; a filler of bioactive glass, apatites, and other (meth)acrylates | KERR CORPORATION | 2002-08-29 | — | — | US | claimed |
| EP-1202701-A1 | DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | JENERIC/PENTRON Incorporated (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001012129-A1 | DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | JENERIC/PENTRON INCORPORATED (US) | 2001-02-22 | — | — | WO | claimed |
| US-7855242-B2 | Dental resin composition, method of manufacture, and method of use thereof | PENTRON CLINICAL TECHNOLOGIES LLC (US) | 2010-12-21 | — | — | US | disclosed |
| US-7700667-B2 | Dental resin composition, method of manufacture, and method of use thereof | PENTRON CLINICAL TECHNOLOGIES, LLC (US) | 2010-04-20 | — | — | US | disclosed |
| US-7275933-B2 | Method of manufacturing dental restorations | PENTRON CLINICAL TECHNOLOGIES, LLC (US) | 2007-10-02 | — | — | US | disclosed |
| US-20070049656-A1 | DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | PENTRON CLINICAL TECHNOLOGIES, INC (US) | 2007-03-01 | — | — | US | disclosed |
| US-20050192374-A1 | Dental resin composition, method of manufacture, and method of use thereof | KERR CORPORATION | 2005-09-01 | — | — | US | disclosed |
| EP-1202701-A1 | DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | JENERIC/PENTRON Incorporated (US) | 2002-05-08 | — | — | EP | disclosed |
| US-6221546-B1 | COMPRISING A WATER INSOLUBLE VINYL OR ACRYLIC POLYMER HAVING A TG LESS THAN 25 DEGREES C | EASTMAN KODAK COMPANY | 2001-04-24 | — | — | US | disclosed |
| WO-2001012129-A1 | DENTAL COMPOSITIONS COMPRISING DEGRADABLE POLYMERS | JENERIC/PENTRON INCORPORATED (US) | 2001-02-22 | — | — | WO | disclosed |
| EP-1069472-A1 | Coating composition for a protecting layer for gelatin based photographic products containing a 1H-pyrazolo-[1,5-b][1,2,4]-triazole-type magenta coupler | EASTMAN KODAK COMPANY (US) | 2001-01-17 | — | — | EP | disclosed |
| EP-1069471-A1 | Coating composition for a protecting layer for image recording materials | EASTMAN KODAK COMPANY (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6165653-A | Protecting layer for gelatin based photographic products containing 1H-pyrazolo[1,5,-b][1,2,4]triazole-type magenta coupler | EASTMAN KODAK COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192374-A1 | Dental resin composition, method of manufacture, and method of use thereof | GRM6, MPHOSPH6, H1-0 | ALDH1A1 2492/4885HPGD 1111/4885KDM4E 723/4885 |
| US-20070049656-A1 | DENTAL RESIN COMPOSITION, METHOD OF MANUFACTURE, AND METHOD OF USE THEREOF | CAD, MMAB, DNMT3A | ALDH1A1 1227/4885HPGD 799/4885KDM4E 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.