SCHEMBL3278424

SCHEMBL3278424

CC1=CC2CC1C(C(=O)O)C2C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
POLB P06746 7/20 0.40
TDP1 Q9NUW8 4/20 0.40
APEX1 P27695 1/20 0.40
ALDH1A1 P00352 4/20 0.39
LMNA P02545 3/20 0.39
KDM4E B2RXH2 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HTT P42858 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CTDSP1 Q9GZU7 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2631734 0.91 POLB (0.41) POLBTDP1APEX1ALDH1A1LMNA
SCHEMBL9743683 0.88 POLB (0.34) POLBTDP1APEX1ALDH1A1LMNA
SCHEMBL10588584 0.88 POLB (0.34) POLBTDP1APEX1ALDH1A1LMNA
SCHEMBL13517077 0.86 POLB (0.41) POLB
SCHEMBL13518155 0.86 POLB (0.41) POLBKDM4EMEN1KMT2A
SCHEMBL11223520 0.85 POLB (0.41) POLBTDP1APEX1ALDH1A1LMNA
SCHEMBL13517960 0.82 SLC6A4 (0.39)
SCHEMBL13517923 0.82 SLC6A4 (0.39)
SCHEMBL13517581 0.79 RAB9A (0.40) POLBALDH1A1LMNAHTTRAB9A
SCHEMBL19204434 0.78 GAA (0.45) POLBTDP1ALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10308563-B2 Process for producing ethylene oligomers HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2019-06-04 US disclosed
EP-2524930-B1 PREPARATION METHOD OF SOLID CATALYST FOR PROPYLENE POLYMERIZATION, AND CATALYST PREPARED THEREBY HANWHA TOTAL PETROCHEMICAL CO LTD (KR) 2018-09-12 EP disclosed
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HANWHA TOTAL PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS HANWHA TOTALENERGIES PETROCHEMICAL CO., LTD. (KR) 2018-06-21 US disclosed
EP-3099738-B1 POLYOLEFIN COPOLYMERS AS COLOUR IMPROVERS IN POLYAMIDES BASF SE (DE) 2017-11-29 EP disclosed
EP-3099738-A1 POLYOLEFIN COPOLYMERS AS COLOR ENHANCERS IN POLYAMIDES BASF SE (DE) 2016-12-07 EP disclosed
US-20160340509-A1 Polyolefin Copolymers as Color Enhancers in Polyamides BASF SE (DE) 2016-11-24 US disclosed
WO-2015110629-A1 POLYOLEFIN COPOLYMERS AS COLOR ENHANCERS IN POLYAMIDES BASF SE (DE) 2015-07-30 WO disclosed
US-9045572-B2 Preparation method of solid catalyst for propylene polymerization and catalyst prepared thereby SAMSUNG TOTAL PETROCHEMICALS CO., LTD. (KR) 2015-06-02 US disclosed
CN-103509142-A Solid catalyst for propylene polymerization and a method for preparation of polypropylene SAMSUNG TOTAL PETROCHEMICALS 2014-01-15 CN disclosed
EP-1669342-A1 METHOD OF SEPARATING STEREOISOMERS OF NORBORNENE, DICARBOXYLIC ACID HAVING NORBORNANE STRUCTURE, OR DERIVATIVE THEREOF Hitachi Chemical Co., Ltd. (JP) 2006-06-14 EP disclosed
US-20040106769-A1 High functional polymers VANTICO INC. AND VANTICO A&T U S INC. (NOW KNOWN AS HUNTSMAN ADVANCED MATERIALS AMERICAS INC.) 2004-06-03 US disclosed
EP-1301553-A2 HIGH FUNCTIONAL POLYMERS Vantico AG (CH) 2003-04-16 EP disclosed
WO-2002004542-A2 HIGH FUNCTIONAL POLYMERS VANTICO AG (CH) 2002-01-17 WO disclosed
EP-0493916-B1 Production of compounds CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
US-5362835-A Production of compounds CIBA-GEIGY CORPORATION (US) 1994-11-08 US disclosed
EP-0503764-A2 Epoxide resins and hardeners CIBA-GEIGY AG (CH) 1992-09-16 EP disclosed
EP-0113042-B1 3,4-DIHYDRO-2H-BENZOPYRAN DERIVATIVES, A METHOD OF PRODUCING THEM, A METHOD OF USING THEM AS STABILIZERS FOR ORGANIC MATERIALS, AND ORGANIC COMPOSITIONS CONTAINING SUCH STABILIZERS KURARAY CO., LTD. (JP) 1989-08-30 EP disclosed
US-4523024-A STABILIZERS FOR ORGANIC MATERIALS SENSITIVE TO HEAT, LIGHT, AND/OR OXIDATIVE FACTORS KURARAY CO., LTD. (JP) 1985-06-11 US disclosed
EP-0113042-A2 3,4-Dihydro-2H-benzopyran derivatives, a method of producing them, a method of using them as stabilizers for organic materials, and organic compositions containing such stabilizers KURARAY CO., LTD. (JP) 1984-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10308563-B2 Process for producing ethylene oligomers OXER1, HAO2, ORC3 POLB 1375/4885TDP1 1797/4885APEX1 410/4885
US-20180169642-A1 CATALYST SYSTEM FOR ETHYLENE OLIGOMERIZATION AND METHOD FOR PRODUCING ETHYLENE OLIGOMERIZATION USING THE SAME HACL2, HAO2, MSMO1 POLB 1591/4885TDP1 2113/4885APEX1 382/4885
US-20180170827-A1 PROCESS FOR PRODUCING ETHYLENE OLIGOMERS OXER1, HAO2, ORC3 POLB 1375/4885TDP1 1797/4885APEX1 410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.