Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278424 | 0.78 | POLB (0.40) | TDP1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL19204355 | 0.77 | TDP1 (0.67) | GAASMN1; SMN2TDP1ALDH1A1MEN1 | |
| SCHEMBL2631734 | 0.74 | POLB (0.41) | SMN1; SMN2TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL13518155 | 0.73 | POLB (0.41) | MEN1KMT2AKDM4EPOLB | |
| SCHEMBL10588584 | 0.71 | POLB (0.34) | SMN1; SMN2TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL13517077 | 0.70 | POLB (0.41) | POLB | |
| SCHEMBL11223520 | 0.69 | POLB (0.41) | TDP1ALDH1A1LMNAPOLB | |
| SCHEMBL30945753 | 0.68 | PPARG (0.36) | GAASMN1; SMN2TSHRALDH1A1MEN1 | |
| SCHEMBL9743683 | 0.68 | POLB (0.34) | SMN1; SMN2TDP1ALDH1A1KDM4ELMNA | |
| SCHEMBL3600320 | 0.67 | GAA (0.71) | GAASMN1; SMN2TDP1CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217879-A1 | PHENYLHYDRAZINE/ANHYDRIDE ADDUCTS AND ANAEROBIC CURABLE COMPOSITIONS USING SAME | HENKEL AG & CO. KGAA (DE) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217879-A1 | PHENYLHYDRAZINE/ANHYDRIDE ADDUCTS AND ANAEROBIC CURABLE COMPOSITIONS USING SAME | AHCY, BAP1, GLO1 | GAA 2944/4885SMN1; SMN2 2004/4885TDP1 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.