Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3277632 | 0.86 | ALDH1A1 (0.31) | — | |
| SCHEMBL13105630 | 0.80 | TMEM97 (0.36) | TMEM97ALOX5 | |
| SCHEMBL7041223 | 0.79 | CACNA1B (0.40) | TMEM97ALOX5 | |
| Hydrochloric Acid SCHEMBL3277033 | 0.79 | TMEM97 (0.35) | TMEM97ALOX5 | |
| SCHEMBL3275975 | 0.74 | — | — | |
| SCHEMBL3277427 | 0.72 | CA12 (0.40) | — | |
| SCHEMBL3111043 | 0.69 | ALDH1A1 (0.40) | TMEM97 | |
| SCHEMBL3111040 | 0.69 | TMEM97 (0.36) | TMEM97ALOX5 | |
| SCHEMBL13120886 | 0.66 | ACHE (0.37) | — | |
| SCHEMBL17369724 | 0.66 | MAOB (0.39) | TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7812039-B2 | analgesic drug for treating neuropathic pain is selected from gabapentine, norvaline, pregabaline, (S)3-isobutylGABA, arginine, thiocitrulline, agmantine, vigabatrin etc. and a NO donar drugs belonging to the classes of aspirin, ibuprofen, paracetamol, naproxen, diclofenac or flurbiprofen | NICOX S.A. (FR) | 2010-10-12 | — | — | US | disclosed |
| US-7696230-B2 | Drugs for chronic pains | NICOX S.A. (FR) | 2010-04-13 | — | — | US | disclosed |
| US-20080113950-A1 | Drugs for chronic pains | NICOX S.A. | 2008-05-15 | — | — | US | disclosed |
| US-20070161576-A1 | Drugs for chronic pains | NICOX S.A. | 2007-07-12 | — | — | US | disclosed |
| US-7199141-B2 | Drugs for chronic pains | NICOX S.A. (FR) | 2007-04-03 | — | — | US | disclosed |
| US-20040171682-A1 | Drugs for chronic pains | NICOX S.A. (FR) | 2004-09-02 | — | — | US | disclosed |
| EP-1417165-A2 | DRUGS FOR CHRONIC PAINS | Nicox S.A. (FR) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003000643-A1 | NITRATE ESTER DERIVATIVES USEFUL FOR PREPARING DRUGS FOR EPILEPSY | NICOX S.A. (FR) | 2003-01-03 | — | — | WO | disclosed |
| WO-2003000642-A2 | DRUGS FOR CHRONIC PAINS | NICOX S.A. (FR) | 2003-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171682-A1 | Drugs for chronic pains | OPRD1, OPRK1, OPRL1 | TMEM97 971/4885ALOX5 500/4885 |
| US-20080113950-A1 | Drugs for chronic pains | OPRD1, OPRL1, OPRK1 | TMEM97 443/4885ALOX5 521/4885 |
| US-20070161576-A1 | Drugs for chronic pains | OPRD1, OPRL1, OPRK1 | TMEM97 1085/4885ALOX5 470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.