Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 14/20 | 0.77 |
| ▸ | RAB9A | P51151 | 14/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 13/20 | 0.77 |
| ▸ | LMNA | P02545 | 5/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.71 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.71 |
| ▸ | RELA | Q04206 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.70 |
| ▸ | IDO1 | P14902 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266299 | 0.91 | NPC1 (0.71) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL3112891 | 0.90 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL30073965 | 0.90 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL1819335 | 0.88 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL2461208 | 0.88 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL1856861 | 0.88 | NPC1 (0.67) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL1818561 | 0.84 | NPC1 (0.73) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL9358641 | 0.84 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL20542573 | 0.84 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL30195363 | 0.82 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9074128-B2 | Metal complexes having azaborol ligands and electronic device having the same | MERCK PATENT GMBH (DE) | 2015-07-07 | — | — | US | disclosed |
| US-8722898-B2 | — | — | 2014-05-13 | — | — | US | disclosed |
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | MERCK PATENT GMBH (DE) | 2012-01-05 | — | — | US | disclosed |
| WO-2010099852-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | MERCK PATENT GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004407-A1 | METAL COMPLEXES HAVING AZABOROL LIGANDS AND ELECTRONIC DEVICE HAVING THE SAME | ICOSLG, ERAL1, CTCF | NPC1 3946/4885RAB9A 2083/4885SMN1; SMN2 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.