Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | CHRND | Q07001 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875142 | 0.87 | L3MBTL1 (0.36) | ALDH1A1MAPK1SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL11465239 | 0.84 | CHRNA1 (0.39) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL13593734 | 0.81 | CHRNA1 (0.41) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL11738097 | 0.78 | ALDH1A1 (0.39) | KDM1ARCOR1ALDH1A1MAPK1CYP1A2 | |
| SCHEMBL14779113 | 0.77 | TSHR (0.47) | ALDH1A1MAPK1SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL855229 | 0.77 | CHRNA1 (0.48) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL3279952 | 0.76 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL8402532 | 0.73 | KDM1A (0.41) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL3129922 | 0.72 | CHRNA1 (0.41) | CHRNA1CHRNGCHRNB1CHRNB2SLC6A2 | |
| SCHEMBL8377615 | 0.72 | ALDH1A1 (0.35) | KDM1ARCOR1ALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55009028-A | — | — | None | — | — | JP | disclosed |
| US-7700657-B2 | Vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-04-20 | — | — | US | disclosed |
| EP-1395538-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2009-12-30 | — | — | EP | disclosed |
| CN-1267394-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2006-08-02 | — | — | CN | disclosed |
| CN-1549803-A | Vitamin D analogues | �������о�����չ˽������˾ | 2004-11-24 | — | — | CN | disclosed |
| US-20040224929-A1 | Novel vitamin D analogs | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-11-11 | — | — | US | disclosed |
| EP-1395538-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2004-03-10 | — | — | EP | disclosed |
| WO-2002094754-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2002-11-28 | — | — | WO | disclosed |
| JP-S559028-A | NOVEL 3'-(ALPHA-HYDROXYBENZYL)-PROPIOPHENONE AND ITS PREPARATION | SHIOIRI TAKAYUKI | 1980-01-22 | — | — | JP | disclosed |