Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.49 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2662937 | 0.83 | GAA (0.57) | ALDH1A1KDM4EIDO1PLOD2PLOD3 | |
| SCHEMBL31326722 | 0.82 | NAPRT (0.65) | ALDH1A1LMNAIDO1PLOD2PLOD3 | |
| SCHEMBL17672056 | 0.82 | NAPRT (0.65) | ALDH1A1LMNAIDO1PLOD2PLOD3 | |
| SCHEMBL11823899 | 0.82 | NPC1 (0.65) | ALDH1A1KDM4ELMNAIDO1PLOD2 | |
| Bromide SCHEMBL11271481 | 0.82 | GAA (0.56) | ALDH1A1KDM4EIDO1PLOD2PLOD3 | |
| SCHEMBL28843895 | 0.82 | NAPRT (0.56) | ALDH1A1KDM4ELMNAIDO1PKM | |
| SCHEMBL9602354 | 0.82 | MEN1 (0.57) | PLOD2PLOD3PLOD1TBXAS1KMT2A | |
| SCHEMBL4090694 | 0.81 | PLOD2 (0.49) | ALDH1A1LMNAIDO1PLOD2PLOD3 | |
| SCHEMBL360711 | 0.81 | PLOD2 (0.69) | ALDH1A1KDM4ELMNAPLOD2PLOD3 | |
| SCHEMBL570730 | 0.81 | MAPT (0.51) | RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2018364-B1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN INC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-7709507-B2 | Therapeutic fluoroethyl ureas | ALLERGAN, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. | 2007-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | SLC14A1, MAPT, UTS2R | ALDH1A1 1278/4885KDM4E 1547/4885LMNA 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.