Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | VNN1 | O95497 | 3/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.52 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.52 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CSF1R | P07333 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602346 | 0.89 | VNN1 (0.61) | MEN1KMT2ATSHRVNN1TBXAS1 | |
| SCHEMBL4024081 | 0.85 | MEN1 (0.51) | MEN1KMT2AVNN1PLOD2PLOD3 | |
| SCHEMBL6970291 | 0.84 | CES2 (0.61) | MEN1KMT2AMAPTCES2 | |
| SCHEMBL28977515 | 0.83 | VNN1 (0.54) | MEN1KMT2ATSHRVNN1MAPT | |
| SCHEMBL423797 | 0.83 | MEN1 (0.62) | MEN1KMT2AVNN1MAPTCES2 | |
| SCHEMBL3281996 | 0.82 | ALDH1A1 (0.54) | MEN1KMT2ATBXAS1PLOD2PLOD3 | |
| SCHEMBL31326722 | 0.79 | NAPRT (0.65) | MEN1KMT2APLOD2PLOD3PLOD1 | |
| SCHEMBL17672056 | 0.79 | NAPRT (0.65) | MEN1KMT2APLOD2PLOD3PLOD1 | |
| SCHEMBL11823899 | 0.79 | NPC1 (0.65) | MEN1KMT2ATSHRPLOD2ALOX15 | |
| SCHEMBL2929610 | 0.79 | VNN1 (0.57) | MEN1KMT2ATSHRVNN1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221601-B1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-10 | — | — | EP | disclosed |
| US-5180832-A | Chemical intermediate for thromboxane A2 inhibitor | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-19 | — | — | US | disclosed |
| US-4746671-A | THROMBOXANE SYNTHETASE INHIBITION | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-05-24 | — | — | US | disclosed |