Benzophenone

Benzophenone

SCHEMBL3282461

C=CC(=O)O.C=CC(=O)O.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.70
AKT1 P31749 1/20 0.62
TDP1 Q9NUW8 2/20 0.58
ATM Q13315 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
SRD5A2 P31213 1/20 0.58
MEN1 O00255 4/20 0.54
KMT2A Q03164 4/20 0.54
LMNA P02545 3/20 0.53
HPGD P15428 2/20 0.53
RAB9A P51151 3/20 0.50
MAPT P10636 2/20 0.50
MAPK13 O15264 1/20 0.50
MAPK12 P53778 1/20 0.50
MAPK11 Q15759 1/20 0.50
MAPK14 Q16539 1/20 0.50
NPC1 O15118 2/20 0.48
PBRM1 Q86U86 1/20 0.48
AKR1C3 P42330 1/20 0.48
DAO P14920 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL260367 1.00 ALDH1A1 (0.70) ALDH1A1AKT1TDP1ATML3MBTL1
Acrylic Acid SCHEMBL15006959 0.89 KMT2A (0.68) ALDH1A1AKT1TDP1ATML3MBTL1
Acrylic Acid SCHEMBL28643745 0.88 ALDH1A1 (0.61) ALDH1A1AKT1SRD5A2MEN1KMT2A
Benzophenone SCHEMBL1884581 0.86 ALDH1A1 (0.64) ALDH1A1AKT1TDP1ATML3MBTL1
Benzoic Acid SCHEMBL2099239 0.85 TSHR (0.70) ALDH1A1AKT1TDP1SRD5A2MEN1
Benzil SCHEMBL542099 0.85 CES2 (0.70) ALDH1A1AKT1TDP1ATMMEN1
Benzoic Acid SCHEMBL30978335 0.85 TSHR (0.70) ALDH1A1AKT1TDP1SRD5A2MEN1
Acrylic Acid SCHEMBL22472204 0.85 AKT1 (0.62) ALDH1A1AKT1TDP1L3MBTL1MEN1
Benzophenone SCHEMBL27962779 0.85 ALDH1A1 (0.70) ALDH1A1AKT1TDP1ATML3MBTL1
Benzophenone SCHEMBL9121611 0.85 ALDH1A1 (0.70) ALDH1A1AKT1TDP1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116589803-A Anti-aging PVC material and synthesis process 揭阳市优士科技实业有限公司 2023-08-15 CN claimed
CN-116589803-A Anti-aging PVC material and synthesis process 揭阳市优士科技实业有限公司 2023-08-15 CN disclosed
CN-109839802-B Photosensitive resin composition containing polymerizable photoinitiator 北京鼎材科技有限公司 2022-11-22 CN disclosed
US-7709545-B2 Benzophenone/thioxanthone derivatives and their use in photopolymerizable compositions THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2010-05-04 US disclosed
WO-2008070737-A1 BENZOPHENONE/THIOXANTHONE DERIVATIVES AND THEIR USE IN PHOTOPOLYMERIZABLE COMPOSITIONS UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2008-06-12 WO disclosed
US-20080132601-A1 BENZOPHENONE/THIOXANTHONE DERIVATIVES AND THEIR USE IN PHOTOPOLYMERIZABLE COMPOSITIONS THE UNIVERSITY OF SOUTHERN MISSISSIPPI 2008-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132601-A1 BENZOPHENONE/THIOXANTHONE DERIVATIVES AND THEIR USE IN PHOTOPOLYMERIZABLE COMPOSITIONS TBXAS1, TYR, PPOX ALDH1A1 1129/4885AKT1 2968/4885TDP1 378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.