SCHEMBL3282879

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31129630	0.83	NUDT1 (0.51)	APPGABRA5GABRPGABRDGABRA1
	SCHEMBL1002563	0.80	APP (0.58)	APPNPC1SMN1; SMN2
	SCHEMBL14745014	0.80	GABRA5 (0.61)	GABRA5CYP2C19NPC1ALOX5CYP3A4
	SCHEMBL204325	0.79	MAOB (0.54)	GABRA5GABRPGABRDGABRA1GABRB1
	SCHEMBL2144103	0.79	MAOB (0.54)	GABRA5GABRPGABRDGABRA1GABRB1
	SCHEMBL17611047	0.79	GABRA5 (0.51)	GABRA5GABRPGABRDGABRA1GABRB1
	SCHEMBL784744	0.79	NPC1 (0.49)	GABRA5GABRPGABRDGABRA1GABRB1
	SCHEMBL3887646	0.79	GABRA5 (0.50)	GABRA5GABRPGABRDGABRA1GABRB1
	SCHEMBL30062389	0.79	MAOB (0.54)	GABRA5GABRPGABRDGABRA1GABRB1
	SCHEMBL14923434	0.78	NUDT1 (0.51)	APPGABRA5GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.