Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3283597 | 0.83 | — | — | |
| SCHEMBL3286411 | 0.78 | CHRM3 (0.31) | CYP2C9CYP2C19 | |
| SCHEMBL3282945 | 0.73 | — | — | |
| SCHEMBL187157 | 0.68 | CYP2C9 (0.33) | CYP2C9CYP2C19 | |
| SCHEMBL3283572 | 0.67 | — | — | |
| SCHEMBL600028 | 0.66 | MAPK1 (0.32) | CYP2C19 | |
| SCHEMBL9309557 | 0.65 | — | — | |
| SCHEMBL14321102 | 0.65 | CYP3A4 (0.35) | — | |
| SCHEMBL20447644 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL9707224 | 0.64 | MAPK1 (0.31) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8258126-B2 | Vitamin D3 analogues for the prevention and treatment of bone disorders | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2012-09-04 | — | — | US | disclosed |
| US-20100160455-A1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | K.U. LEUVEN RESEARCH AND DEVELOPMENT (BE) | 2010-06-24 | — | — | US | disclosed |
| US-7704986-B2 | 5-(((3-((4-Hydroxy,1,5-dimethylhexyl)-2,2,3-(trimethyl)cyclopentyl)-2-propenylidene)cyclohexane-1,3-diol; induce bone matrix formation; mineralization without hypercalcemia; side effect reduction; bone disorders; osteomalacia, renal osteodystrophy, Paget's disease and osteoporosis; skin disorders | K.U. LEUVEN RESEARCH AND DEVELOPMENT (BE) | 2010-04-27 | — | — | US | disclosed |
| EP-1809599-B1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | LEUVEN K U RES & DEV (BE) | 2008-12-10 | — | — | EP | disclosed |
| US-20080032955-A1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | K.U. LEUVEN RESEARCH AND DEVELOPMENT (BE) | 2008-02-07 | — | — | US | disclosed |
| EP-1809599-A1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | K.U.Leuven Research & Development (BE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006039763-A1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160455-A1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | VDR, CYP24A1, CYP2R1 | CYP2C9 4210/4885CYP2C19 3287/4885 |
| US-20080032955-A1 | VITAMIN D3 ANALOGUES FOR THE PREVENTION AND TREATMENT OF BONE DISORDERS | VDR, CYP24A1, CYP2R1 | CYP2C9 4210/4885CYP2C19 3287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.