Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554779 | 0.78 | PDE2A (0.32) | — | |
| SCHEMBL630411 | 0.77 | PLAU (0.35) | — | |
| SCHEMBL20526087 | 0.76 | CES2 (0.35) | CES2 | |
| SCHEMBL454940 | 0.76 | CES2 (0.35) | CES2 | |
| SCHEMBL28001125 | 0.76 | TSHR (0.35) | CES2 | |
| SCHEMBL17434720 | 0.74 | CES2 (0.34) | CES2 | |
| SCHEMBL2747437 | 0.74 | CES2 (0.34) | CES2 | |
| SCHEMBL7701994 | 0.72 | CYP11B1 (0.36) | CES2NOTUM | |
| SCHEMBL29044683 | 0.71 | ALDH1A1 (0.43) | — | |
| SCHEMBL19002930 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185059-A1 | Antiallergic agents | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2007-08-09 | — | — | US | claimed |
| US-9580444-B2 | Polycyclic pyrazolinone derivative and herbicide comprising same as effective component thereof | SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) | 2017-02-28 | — | — | US | disclosed |
| EP-2744788-B1 | BENZOPIPERAZINE DERIVATIVES AS CETP INHIBITORS | MERCK SHARP & DOHME (US) | 2016-10-19 | — | — | EP | disclosed |
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2016-01-28 | — | — | US | disclosed |
| EP-2975040-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | Sagami Chemical Research Institute (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-9126976-B2 | Substituted benzopiperazines as CETP inhibitors | MERCK SHARP & DOHME CORP. (US) | 2015-09-08 | — | — | US | disclosed |
| US-20140357632-A1 | BENZOPIPERAZINE DERIVATIVES AS CETP INHIBITORS | MERCK SHARP & DOHME LLC | 2014-12-04 | — | — | US | disclosed |
| EP-2744788-A1 | BENZOPIPERAZINE DERIVATIVES AS CETP INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2014-06-25 | — | — | EP | disclosed |
| CN-103864754-A | Five-membered azole heterocycle compound, preparation method, drug composition and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-06-18 | — | — | CN | disclosed |
| WO-2013028382-A1 | BENZOPIPERAZINE DERIVATIVES AS CETP INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2013-02-28 | — | — | WO | disclosed |
| US-6878663-B2 | Method for producing palladium complex compound | CENTRAL GLASS COMPANY, LIMITED (JP) | 2005-04-12 | — | — | US | disclosed |
| EP-1514544-A1 | ANTIALLERGIC | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-16 | — | — | EP | disclosed |
| EP-1512396-A1 | INHIBITORS AGAINST THE ACTIVATION OF AP-1 AND NFAT | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1008601-B1 | Method for producing palladium complex compound | CENTRAL GLASS CO LTD (JP) | 2005-03-09 | — | — | EP | disclosed |
| EP-1510210-A1 | IMMUNITY-RELATED PROTEIN KINASE INHIBITORS | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-02 | — | — | EP | disclosed |
| EP-1510207-A1 | THERAPEUTIC DRUG FOR DIABETES | Institute of Medicinal Molecular Design, Inc. (JP) | 2005-03-02 | — | — | EP | disclosed |
| US-6706905-B1 | REACTING AROMATIC COMPOUND, PALLADIUM(II) COMPOUND, AND PHOSPHINE DERIVATIVE; COMPLEXING WITH BENZOIC ACID DERIVATIVE; METALLIZATION | CENTRAL GLASS COMPANY, LIMITED (JP) | 2004-03-16 | — | — | US | disclosed |
| US-20020111482-A1 | Method for producing palladium complex compound | CENTRAL GLASS COMPANY, LIMITED | 2002-08-15 | — | — | US | disclosed |
| EP-1008601-A2 | Method for producing palladium complex compound | Central Glass Company, Limited (JP) | 2000-06-14 | — | — | EP | disclosed |
| WO-1995033711-A1 | PHENYL BENZOYL(NICOTINOYL) UREA DERIVATIVES | HANWHA CORPORATION (KR) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024110-A1 | POLYCYCLIC PYRAZOLINONE DERIVATIVE AND HERBICIDE COMPRISING SAME AS EFFECTIVE COMPONENT THEREOF | DDT, PDHX, CYP4X1 | CES2 673/4885NOTUM 201/4885 |
| US-20020111482-A1 | Method for producing palladium complex compound | PDCD1LG2, CD274, PDCD1 | CES2 3861/4885NOTUM 3871/4885 |
| US-20140357632-A1 | BENZOPIPERAZINE DERIVATIVES AS CETP INHIBITORS | CETP, MTTP, HDLBP | CES2 158/4885NOTUM 295/4885 |
| US-20070185059-A1 | Antiallergic agents | NAT1, EPX, AHR | CES2 1509/4885NOTUM 1888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.