SCHEMBL454940

SCHEMBL454940

FC(F)(F)c1c[c]c(C(F)(F)F)c(C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20526087 0.77 CES2 (0.35) CES2
SCHEMBL17238705 0.76 PLAU (0.36)
SCHEMBL17434720 0.76 CES2 (0.34) CES2
SCHEMBL2747437 0.76 CES2 (0.34) CES2
SCHEMBL3284587 0.76 CES2 (0.34) CES2
SCHEMBL6221853 0.71 CACNA1H (0.33) CES2
SCHEMBL17238699 0.71 CES2 (0.32) CES2
SCHEMBL8995621 0.70 CES2 (0.31) CES2
SCHEMBL8480518 0.69 CES2 (0.33) CES2
SCHEMBL8478612 0.69 KDM4E (0.32) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2190466-A2 TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP) ACTIVATORS AND USES THEREOF Burnham Institute for Medical Research (US) 2010-06-02 EP claimed
WO-2009042294-A2 TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP) ACTIVATORS AND USES THEREOF BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2009-04-02 WO claimed
US-20090053192-A1 TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP) ACTIVATORS AND USES THEREOF BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) 2009-02-26 US claimed
EP-0972764-A1 Aminoalcohols and aminoketones as CNS active agents Universita Degli Studi di Firenze (IT) 2000-01-19 EP claimed
EP-4394981-A1 NONAQUEOUS ELECTROLYTE AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-07-03 EP disclosed
EP-4006040-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND LIGHTING DEVICE Toray Industries, Inc. (JP) 2022-06-01 EP disclosed
US-20210061821-A1 PYRROMETHENE BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, ILLUMINATION APPARATUS, AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2021-03-04 US disclosed
US-10907094-B2 Pyrromethene-boron complex, color conversion composition, color conversion film, light source unit, display, and illumination apparatus TORAY INDUSTRIES, INC. (JP) 2021-02-02 US disclosed
US-20190345380-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND ILLUMINATION APPARATUS TORAY INDUSTRIES, INC. (JP) 2019-11-14 US disclosed
EP-3550206-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND ILLUMINATION DEVICE Toray Industries, Inc. (JP) 2019-10-09 EP disclosed
CN-109996802-A Methylene pyrrole boron complex, color shifting combination object, color conversion film, light source unit, display and lighting device 东丽株式会社 2019-07-09 CN disclosed
EP-3045450-B1 INTERMEDIATE COMPOUNDS IN PROCESSES FOR PRODUCING PYRIDAZINONE COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2018-02-07 EP disclosed
EP-1442067-A1 SOLID COCATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST SYSTEM THEREOF Sunallomer Ltd (JP) 2004-08-04 EP disclosed
EP-1426374-A1 NAPHTHYRIDINE DERIVATIVE OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) 2004-06-09 EP disclosed
US-20040054102-A1 Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer SUNALLOMER LTD. (JP) 2004-03-18 US disclosed
US-6706905-B1 REACTING AROMATIC COMPOUND, PALLADIUM(II) COMPOUND, AND PHOSPHINE DERIVATIVE; COMPLEXING WITH BENZOIC ACID DERIVATIVE; METALLIZATION CENTRAL GLASS COMPANY, LIMITED (JP) 2004-03-16 US disclosed
EP-1359166-A1 OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD OF STORING THESE, AND PROCESS FOR PRODUCING OLEFIN POLYMER Sunallomer Ltd (JP) 2003-11-05 EP disclosed
WO-2003035708-A1 SOLID COCATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST SYSTEM THEREOF SUNALLOMER LTD (JP) 2003-05-01 WO disclosed
US-20020111482-A1 Method for producing palladium complex compound CENTRAL GLASS COMPANY, LIMITED 2002-08-15 US disclosed
EP-1008601-A2 Method for producing palladium complex compound Central Glass Company, Limited (JP) 2000-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10907094-B2 Pyrromethene-boron complex, color conversion composition, color conversion film, light source unit, display, and illumination apparatus CD79B, BLVRB, CRY1 CES2 2695/4885
US-20020111482-A1 Method for producing palladium complex compound PDCD1LG2, CD274, PDCD1 CES2 3861/4885
US-20210061821-A1 PYRROMETHENE BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, ILLUMINATION APPARATUS, AND LIGHT-EMITTING DEVICE CRY1, CD79B, BLVRB CES2 2850/4885
US-20090053192-A1 TISSUE-NONSPECIFIC ALKALINE PHOSPHATASE (TNAP) ACTIVATORS AND USES THEREOF ALPL, ALPP, ACP3 CES2 2365/4885
US-20190345380-A1 PYRROMETHENE-BORON COMPLEX, COLOR CONVERSION COMPOSITION, COLOR CONVERSION FILM, LIGHT SOURCE UNIT, DISPLAY, AND ILLUMINATION APPARATUS CD79B, BLVRB, CRY1 CES2 2695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.