Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959640 | 1.00 | KMT2A (0.51) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL165769 | 0.83 | KMT2A (0.54) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL23051074 | 0.82 | SLC29A1 (0.37) | KMT2AMEN1ALDH1A1HPGDHRH3 | |
| SCHEMBL26784221 | 0.81 | KMT2A (0.46) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL165770 | 0.81 | KMT2A (0.53) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL167209 | 0.80 | KMT2A (0.51) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL23870859 | 0.80 | KMT2A (0.49) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL15160661 | 0.80 | ATM (0.54) | KMT2AMEN1ALDH1A1L3MBTL1BCHE | |
| SCHEMBL10386591 | 0.79 | KMT2A (0.51) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL5111511 | 0.79 | KMT2A (0.51) | KMT2AMEN1ALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |