Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582224 | 0.74 | RECQL (0.39) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL10149607 | 0.74 | RECQL (0.39) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL31531962 | 0.72 | ALDH1A1 (0.46) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL17010360 | 0.71 | MAPT (0.49) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL12268038 | 0.69 | ALDH1A1 (0.70) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL28716123 | 0.65 | RAB9A (0.53) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL14998060 | 0.64 | ALDH1A1 (0.42) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL9419538 | 0.63 | ALDH1A1 (0.41) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL16116063 | 0.63 | RECQL (0.58) | RECQLALDH1A1GAAMAPTUSP2 | |
| SCHEMBL16116072 | 0.63 | RECQL (0.58) | RECQLALDH1A1GAAMAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428509-A1 | Human adam-10 inhibitors | Symphony Evolution, Inc. (US) | 2012-03-14 | — | — | EP | disclosed |