Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MC4R | P32245 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | MC3R | P41968 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | MAP2K3 | P46734 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22544545 | 0.81 | SIRT6 (0.39) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL27729620 | 0.81 | ALDH1A1 (0.44) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL28344636 | 0.77 | SIRT6 (0.44) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL30145632 | 0.77 | SIRT6 (0.44) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL28344658 | 0.77 | SIRT6 (0.39) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL28347446 | 0.75 | HSP90AA1 (0.40) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2635320 | 0.75 | SIRT6 (0.73) | SIRT6ADORA3TSHRMC4RADRA1A | |
| Hydrochloric Acid SCHEMBL27917292 | 0.72 | SIRT6 (0.70) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL18230703 | 0.72 | SCN9A (0.37) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL30441778 | 0.71 | SIRT6 (0.46) | SIRT6ADORA3TSHRMC4RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618756-B2 | Photoconductors containing chelating components | XEROX CORPORATION (US) | 2009-11-17 | — | — | US | claimed |
| US-20080220352-A1 | Photoconductors containing chelating components | XEROX CORPORATION | 2008-09-11 | — | — | US | claimed |
| CN-109069649-A | Compositions and methods for treating nasal and paranasal mucosal disorders with nicotinic acetylcholine receptor agonists | A·索利斯·赫雷拉 | 2018-12-21 | — | — | CN | disclosed |
| US-7718336-B2 | Photoconductors containing photogenerating chelating components | XEROX CORPORATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-20080220351-A1 | Photoconductors containing photogenerating chelating components | XEROX CORPORATION | 2008-09-11 | — | — | US | disclosed |