Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22216377 | 1.00 | MGAM (0.42) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL22216156 | 0.98 | MGAM (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL22323081 | 0.94 | GAA (0.45) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6499787 | 0.81 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1KDM4ENPC1PDE2A | |
| SCHEMBL16935877 | 0.81 | PYGL (0.43) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL3188799 | 0.81 | TSHR (0.39) | ALDH1A1L3MBTL1SMYD3LMNAKMT2A | |
| SCHEMBL11434281 | 0.80 | GAA (0.48) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL6495211 | 0.80 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1PDE2APDE3BPDE3A | |
| SCHEMBL4442140 | 0.79 | KMT2A (0.46) | ALDH1A1L3MBTL1LMNANPSR1KMT2A | |
| SCHEMBL31126845 | 0.79 | CYP1A2 (0.41) | ALDH1A1L3MBTL1KDM4ENPC1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420637-B2 | Abnormal cannabidiols as agents for lowering intraocular pressure | ALLERGAN, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-7718830-B2 | Abnormal cannabidiols as agents for lowering intraocular pressure | ALLERGAN, INC. (US) | 2010-05-18 | — | — | US | disclosed |
| US-20100010027-A1 | ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN, INC. | 2010-01-14 | — | — | US | disclosed |
| US-7618966-B2 | Abnormal Cannabidiols as agents for lowering intraocular pressure | ALLERGAN, INC. (US) | 2009-11-17 | — | — | US | disclosed |
| US-7612101-B2 | Abnormal cannabidiols as agents for lowering intraocular pressure | ALLERGAN, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20070249731-A1 | Abnormal cannabidiols as agents for lowering intraocular pressure | ALLERGAN, INC. | 2007-10-25 | — | — | US | disclosed |
| US-20070249581-A1 | Abnormal Cannabidiols as agents for lowering intraocular pressure | ALLERGAN, INC. | 2007-10-25 | — | — | US | disclosed |
| US-20070249602-A1 | 4-(1-isopropyl-4-methyl-1,2,5,6-tetra-hydropyridin-2-yl)-5-methylbenzene- 1,3-diol; glaucoma or ocular hypertension | ALLERGAN, INC. | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249581-A1 | Abnormal Cannabidiols as agents for lowering intraocular pressure | CNR2, CNR1, PTGIR | MGAM 4352/4885GAA 4467/4885SI 4865/4885 |
| US-20070249731-A1 | Abnormal cannabidiols as agents for lowering intraocular pressure | CNR2, CNR1, PTGIR | MGAM 4352/4885GAA 4467/4885SI 4865/4885 |
| US-20070249602-A1 | 4-(1-isopropyl-4-methyl-1,2,5,6-tetra-hydropyridin-2-yl)-5-methylbenzene- 1,3-diol; glaucoma or ocular hypertension | PTGIR, PTGS1, PTGIS | MGAM 4677/4885GAA 4377/4885SI 4849/4885 |
| US-20100010027-A1 | ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | CNR2, CNR1, PTGIR | MGAM 4352/4885GAA 4467/4885SI 4865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.