Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6495211 | 0.99 | ALDH1A1 (0.39) | ALDH1A1PDE3BPDE3ANFKB1NFKB2 | |
| SCHEMBL6501399 | 0.97 | NFKB1 (0.39) | ALDH1A1PDE3BPDE3ANFKB1NFKB2 | |
| SCHEMBL6488909 | 0.93 | NFKB1 (0.39) | ALDH1A1PDE3BPDE3ANFKB1NFKB2 | |
| SCHEMBL20408343 | 0.87 | ALDH1A1 (0.37) | ALDH1A1PDE3BPDE3ANFKB1NFKB2 | |
| SCHEMBL14095485 | 0.85 | ALDH1A1 (0.41) | ALDH1A1PDE3BPDE3ANFKB1NFKB2 | |
| SCHEMBL15297743 | 0.84 | GPR119 (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL15370101 | 0.83 | NFKB1 (0.40) | ALDH1A1PDE3BPDE3ANFKB1NFKB2 | |
| SCHEMBL9200042 | 0.83 | KDM5A (0.38) | ALDH1A1L3MBTL1 | |
| SCHEMBL13494079 | 0.83 | ADH1A (0.41) | ALDH1A1NFKB1NFKB2RELAL3MBTL1 | |
| SCHEMBL22216377 | 0.81 | MGAM (0.42) | ALDH1A1PDE3BPDE3AL3MBTL1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1890703-B1 | PYRIMIDINE COMPOUNDS AS CHEMOKINE RECEPTORS INHIBITORS | TAIGEN BIOTECHNOLOGY CO LTD (TW) | 2016-05-11 | — | — | EP | disclosed |
| US-8193206-B2 | Pyrimidine compounds | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2012-06-05 | — | — | US | disclosed |
| US-7589197-B2 | Pyrimidine compounds | TAIGEN BIOTECHNOLOGY (TW) | 2009-09-15 | — | — | US | disclosed |
| US-20090143302-A1 | PYRIMIDINE COMPOUNDS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2009-06-04 | — | — | US | disclosed |
| US-6903107-B1 | Serine protease inhibitor | AKZO NOBEL N.V. (NL) | 2005-06-07 | — | — | US | disclosed |
| EP-1123280-A1 | SERINE PROTEASE INHIBITOR | Akzo Nobel N.V. (NL) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024718-A1 | SERINE PROTEASE INHIBITOR | AKZO NOBEL N.V. (NL) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143302-A1 | PYRIMIDINE COMPOUNDS | TYMS, TYMP, HPRT1 | ALDH1A1 402/4885PDE3B 2103/4885PDE3A 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.