Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13102160 | 0.78 | MCHR1 (0.41) | MCHR1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL8350573 | 0.78 | MC4R (0.44) | MCHR1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL2717162 | 0.74 | — | — | |
| SCHEMBL13123466 | 0.74 | — | — | |
| SCHEMBL8438966 | 0.73 | HPGD (0.39) | MCHR1HPGDMEN1KMT2ATDP1 | |
| SCHEMBL1628917 | 0.73 | — | — | |
| SCHEMBL6421867 | 0.72 | MEN1 (0.52) | HPGDMEN1KMT2ATDP1TSHR | |
| SCHEMBL5069114 | 0.72 | CA1 (0.51) | MAPT | |
| SCHEMBL8436149 | 0.70 | GAA (0.63) | MEN1KMT2ATDP1MAOAALDH1A1 | |
| SCHEMBL19145053 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258708-A1 | Macrolide compounds endowed with antiinflammatory activity | Zambon S.p.A. (IT) | 2010-12-08 | — | — | EP | disclosed |
| US-7704960-B2 | Macrolide compounds endowed with antiinflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2010-04-27 | — | — | US | disclosed |
| US-20090054357-A1 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2009-02-26 | — | — | US | disclosed |
| US-7488811-B2 | Macrolide compounds endowed with antiinflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2009-02-10 | — | — | US | disclosed |
| US-20060058246-A1 | Macrolide compounds endowed with antiinflammatory activity | ZAMBON GROUP S.P.A. (IT) | 2006-03-16 | — | — | US | disclosed |
| EP-1529053-A2 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004013153-A2 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 2004-02-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054357-A1 | MACROLIDE COMPOUNDS ENDOWED WITH ANTIINFLAMMATORY ACTIVITY | CEL, MPO, IL6 | MCHR1 1781/4885HPGD 2752/4885MEN1 4049/4885 |
| US-20060058246-A1 | Macrolide compounds endowed with antiinflammatory activity | CEL, MPO, IL6 | MCHR1 1781/4885HPGD 2752/4885MEN1 4049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.