SCHEMBL14222708

SCHEMBL14222708

Nc1nc2c(O)cccc2[nH]1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 3/20 0.51
MASP2 O00187 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48
AOC3 Q16853 1/20 0.48
ATR Q13535 1/20 0.47
PLAU P00749 2/20 0.46
NCF1 P14598 1/20 0.46
CDK5 Q00535 4/20 0.45
CDK5R1 Q15078 4/20 0.45
ACHE P22303 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2B Q13224 1/20 0.43
PDPK1 O15530 1/20 0.43
MGAM O43451 2/20 0.42
GAA P10253 2/20 0.42
SI P14410 2/20 0.42
MGAM2 Q2M2H8 2/20 0.42
ULK1 O75385 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Carbamate SCHEMBL6314901 0.86 PARP1 (0.42) NUDT1ATRGRIN1GRIN2B
SCHEMBL4314003 0.79 ACHE (0.46) ALDH1A1KMT2AATRPLAUNCF1
SCHEMBL30291834 0.79 MEN1 (0.58) NUDT1MASP2MEN1ALDH1A1KMT2A
SCHEMBL3287778 0.79 MEN1 (0.58) NUDT1MASP2MEN1ALDH1A1KMT2A
SCHEMBL1042351 0.78 PLAUR (0.54) MEN1KMT2AATRPLAUNCF1
Bromide SCHEMBL11628987 0.78 ACHE (0.45) ALDH1A1KMT2AATRPLAUNCF1
Bromide SCHEMBL5141524 0.77 PLAUR (0.53) MEN1KMT2AATRPLAUNCF1
SCHEMBL9305483 0.76 RAB9A (0.50) ALDH1A1KMT2AATRACHEGRIN1
SCHEMBL3884588 0.76 PARP1 (0.59) ALDH1A1ACHEGRIN1GRIN2BMGAM
SCHEMBL3986301 0.76 ACHE (0.43) ALDH1A1KMT2AATRPLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3611224-A1 COMPOSITION, COMPOSITE FILM AND MEMBRANE ELECTRODE ASSEMBLY ASAHI KASEI KABUSHIKI KAISHA (JP) 2020-02-19 EP disclosed
CN-110366576-A Composition, composite membrane, membrane-electrode assembly 旭化成株式会社 2019-10-22 CN disclosed
WO-2008042282-A2 IMIDAZOLE-4, 5-DICARBOXAMIDE DERIVATIVES AS JAK-2 MODULATORS EXELIXIS, INC. (US) 2008-04-10 WO disclosed