Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 13/20 | 0.53 |
| ▸ | GAA | P10253 | 13/20 | 0.53 |
| ▸ | SI | P14410 | 13/20 | 0.53 |
| ▸ | MGAM2 | Q2M2H8 | 13/20 | 0.53 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.48 |
| ▸ | ATP4B | P51164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL6323883 | 0.90 | ALDH1A1 (0.54) | MGAMGAASIMGAM2NUDT1 | |
| SCHEMBL1170892 | 0.79 | MGAM (0.71) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL353891 | 0.79 | PARP1 (0.56) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL3287778 | 0.79 | MEN1 (0.58) | GAANUDT1MASP2MEN1ALDH1A1 | |
| SCHEMBL30291834 | 0.79 | MEN1 (0.58) | GAANUDT1MASP2MEN1ALDH1A1 | |
| Bromide SCHEMBL5318091 | 0.78 | PARP1 (0.55) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL6139625 | 0.76 | MGAM (0.60) | MGAMGAASIMGAM2ESR1 | |
| SCHEMBL979914 | 0.76 | NUDT1 (0.51) | GAANUDT1MASP2MEN1ALDH1A1 | |
| SCHEMBL14222708 | 0.76 | NUDT1 (0.51) | MGAMGAASIMGAM2NUDT1 | |
| SCHEMBL17276019 | 0.76 | NUDT1 (0.51) | NUDT1MASP2MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | claimed |
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-05-30 | — | — | US | claimed |
| WO-2011102966-A2 | QUASI-SOLID-STATE PHOTOELECTROCHEMICAL SOLAR CELL FORMED USING INKJET PRINTING AND NANOCOMPOSITE ORGANIC-INORGANIC MATERIAL | BRITE HELLAS AE (GR) | 2011-08-25 | — | — | WO | claimed |
| US-20210128561-A1 | MRGX Receptor Antagonists | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2021-05-06 | — | — | US | disclosed |
| US-20210128561-A1 | MRGX Receptor Antagonists | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2021-05-06 | — | — | US | disclosed |
| EP-3313832-B1 | 3-TETRAZOLYL-BENZENE-1,2-DISULFONAMIDE DERIVATIVES AS METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME (US) | 2021-02-24 | — | — | EP | disclosed |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | disclosed |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-05-21 | — | — | US | disclosed |
| CN-106414448-B | It can be used as the new compound of S100- inhibitor | 活跃生物技术有限公司 | 2019-04-19 | — | — | CN | disclosed |
| US-20180094119-A1 | METHOD OF PRODUCING AMINE ADDUCT OF CONDUCTIVE COMPOSITE, METHOD OF PRODUCING AMINE ADDUCT LIQUID OF CONDUCTIVE COMPOSITE, AND METHOD OF PRODUCING CONDUCTIVE FILM | NISSIN CHEMICAL INDUSTRY CO., LTD (JP) | 2018-04-05 | — | — | US | disclosed |
| US-9839642-B2 | Beta-tetrazolyl-propionic acids as metallo-beta-lactamase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-12-12 | — | — | US | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |
| EP-1416931-A1 | INHIBITORS OF POLYQ-AGGREGATION | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003015772-A1 | INHIBITORS OF POLYQ-AGGREGATION | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003000682-A1 | (PYRIMIDYL)(PHENYL)SUBSTITUTED FUSED HETEROARYL P38 INHIBITING AND PKG KINASE INHIBITING COMPOUNDS | MERCK & CO., INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| EP-1246823-A1 | PYRIMIDINE AND TRIAZINE KINASE INHIBITORS | PHARMACOPEIA, INC. (US) | 2002-10-09 | — | — | EP | disclosed |
| WO-2001047921-A1 | PYRIMIDINE AND TRIAZINE KINASE INHIBITORS | PHARMACOPEIA, INC. (US) | 2001-07-05 | — | — | WO | disclosed |
| WO-2000078726-A1 | IMIDAZOLINE DERIVATIVES FOR THE TREATMENT OF DIABETES, ESPECIALLY TYPE II DIABETES | ELI LILLY AND COMPANY (US) | 2000-12-28 | — | — | WO | disclosed |
| EP-0079859-A1 | Method of bulk dyeing organic polymers | CIBA-GEIGY AG (CH) | 1983-05-25 | — | — | EP | disclosed |
| US-3981886-A | Amino-benzimidazole derivatives | E. R. SQUIBB & SONS, INC. (US) | 1976-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130136782-A1 | Inhibition and Dispersion of Bacterial Biofilms with 2-Aminobenzimidazole Derivatives | FLNB, BRI3BP, CCNI | MGAM 132/4885GAA 1314/4885SI 2195/4885 |
| US-10292390-B2 | Inhibition and dispersion of bacterial biofilms with 2-aminobenzimidazole derivatives | FLNB, BRI3BP, CCNI | MGAM 132/4885GAA 1314/4885SI 2195/4885 |
| US-20210128561-A1 | MRGX Receptor Antagonists | MRGPRX2, MRGPRX1, MRGPRX4 | MGAM 1735/4885GAA 934/4885SI 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.