Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.41 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.41 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
| ▸ | CLK2 | P49760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzimidazole SCHEMBL9773841 | 0.83 | ALDH1A1 (0.72) | NUDT1ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL30291834 | 0.82 | MEN1 (0.58) | NUDT1ALDH1A1MEN1KMT2AMASP2 | |
| SCHEMBL3287778 | 0.82 | MEN1 (0.58) | NUDT1ALDH1A1MEN1KMT2AMASP2 | |
| Benzimidazole SCHEMBL6583807 | 0.81 | PRKCI (0.52) | NUDT1ALDH1A1MEN1KMT2AMASP2 | |
| Benzimidazole SCHEMBL5404384 | 0.75 | PRKCI (0.52) | NUDT1ALDH1A1MEN1KMT2AMASP2 | |
| Benzimidazole SCHEMBL29358377 | 0.75 | — | — | |
| Benzimidazole SCHEMBL461969 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1MAPTGAATDP1PRKCI | |
| Benzimidazole SCHEMBL6009 | 0.75 | — | — | |
| Benzimidazole SCHEMBL29408372 | 0.75 | — | — | |
| Benzimidazole SCHEMBL10931770 | 0.75 | SMN1; SMN2 (0.50) | ALDH1A1MAPTGAATDP1PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057667-A2 | STRAPPED AND MODIFIED BIS (BENZIMIDAZOLE) DIAMIDES FOR ASYMMETRIC CATALYSTS AND OTHER APPLICATIONS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-07-17 | — | — | WO | disclosed |