SCHEMBL328791

SCHEMBL328791

NCCCCCCCCCCC(O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 17/20 1.00
PDE3A Q14432 2/20 0.83
LMNA P02545 2/20 0.67
ADRB3 P13945 1/20 0.67
PDE4D Q08499 1/20 0.67
GGPS1 O95749 6/20 0.63
SMPD1 P17405 2/20 0.45
CYP3A4 P08684 1/20 0.41
NFKB1 P19838 1/20 0.41
BLM P54132 1/20 0.41
PMP22 Q01453 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL328859 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
Neridronic Acid SCHEMBL87499 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL6668742 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL6665992 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL3287859 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL12821674 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL6667604 1.00 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D
Neridronic Acid SCHEMBL328773 0.98 FDPS (0.96) FDPSPDE3ALMNAADRB3PDE4D
Neridronic Acid SCHEMBL10776647 0.98 FDPS (0.96) FDPSPDE3ALMNAADRB3PDE4D
SCHEMBL3411395 0.98 FDPS (1.00) FDPSPDE3ALMNAADRB3PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3346969-B1 RADICALLY POLYMERIZABLE DENTAL MATERIAL MUEHLBAUER TECH GMBH (DE) 2021-07-14 EP disclosed
EP-2438076-B1 TARGETED DRUG DELIVERY TO THE BONE UNIV NANYANG TECH (SG) 2018-12-19 EP disclosed
EP-3346969-A1 RADICALLY POLYMERIZABLE DENTAL MATERIAL Mühlbauer Technology GmbH (DE) 2018-07-18 EP disclosed
US-8933058-B2 Targetted drug delivery to the bone NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2015-01-13 US disclosed
US-20140263071-A1 METHOD FOR COLLECTING METALS CHEMEC OY AB (FI) 2014-09-18 US disclosed
US-8404144-B2 Compositions including polymerizable bisphosphonic acids and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-03-26 US disclosed
US-8293029-B2 Colored conversion layers on metal surfaces HENKEL AG & CO. KGAA (DE) 2012-10-23 US disclosed
US-20120142641-A1 TARGETTED DRUG DELIVERY TO THE BONE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2012-06-07 US disclosed
EP-2438076-A1 TARGETTED DRUG DELIVERY TO THE BONE Nanyang Technological University (SG) 2012-04-11 EP disclosed
EP-2407142-A1 Use of polymerizable bisphosphonic acids for the treatment of tooth surfaces that are not pretreated with phosphoric acid 3M Innovative Properties Company (US) 2012-01-18 EP disclosed
US-20090214883-A1 CHROMIUM-FREE, THERMALLY CURABLE CORROSION PROTECTION COMPOSITION HENKEL AG & CO. KGAA (DE) 2009-08-27 US disclosed
US-20090075239-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY 2009-03-19 US disclosed
US-20060173099-A1 Colored conversion layers on metal surfaces HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2006-08-03 US disclosed
EP-1578377-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M Innovative Properties Company (US) 2005-09-28 EP disclosed
US-20040206932-A1 Compositions including polymerizable bisphosphonic acids and methods 3M INNOVATIVE PROPERTIES COMPANY 2004-10-21 US disclosed
WO-2004060327-A1 COMPOSITIONS INCLUDING POLYMERIZABLE BISPHOSPHONIC ACIDS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-07-22 WO disclosed
EP-0452345-A1 PROCESS FOR IMPREGNATING ANODIZED ALUMINIUM SURFACES Henkel Kommanditgesellschaft auf Aktien (DE) 1991-10-23 EP disclosed
WO-1990007589-A1 PROCESS FOR IMPREGNATING ANODIZED ALUMINIUM SURFACES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-07-12 WO disclosed
EP-0141200-B1 DIHYDROXYALKANEDIPHOSPHONIC ACIDS Henkel Kommanditgesellschaft auf Aktien (DE) 1988-07-27 EP disclosed
US-4536348-A OUTSTANDING COMPLEXING POWER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1985-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120142641-A1 TARGETTED DRUG DELIVERY TO THE BONE SOST, BMP6, BMP2 FDPS 346/4885PDE3A 1721/4885LMNA 2146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.