Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 6/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | TGM1 | P22735 | 1/20 | 0.30 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propene SCHEMBL27725465 | 0.90 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1PHF8 | |
| Cyclopropane SCHEMBL11144471 | 0.90 | TSHR (0.44) | TSHRALDH1A1MAPK1TDP1PHF8 | |
| SCHEMBL3652807 | 0.81 | TSHR (0.44) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| SCHEMBL27725463 | 0.80 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1PHF8 | |
| SCHEMBL5054226 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL2918034 | 0.77 | TSHR (0.39) | TSHRALDH1A1MAPK1TDP1TGM2 | |
| Hydrochloric Acid SCHEMBL5487748 | 0.73 | ZDHHC20 (0.40) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL9147096 | 0.72 | PHF8 (0.33) | ALDH1A1PHF8KDM2A | |
| Hydrochloric Acid SCHEMBL15271262 | 0.71 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL176022 | 0.70 | ZDHHC20 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447657-A | Modified polymeric resin applied to drilling fluid collapse-preventing inhibitor and preparation method thereof | 任丘市东顺化工有限公司 | 2024-01-26 | — | — | CN | claimed |
| CN-114642640-B | Microsphere and preparation method and preparation system thereof | 杭州旸顺医疗科技有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-114642640-A | Microsphere, preparation method and preparation system thereof, composition and shearing device | 杭州旸顺医疗科技有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-107722661-A | A kind of periodically degradable plantation, cultivation protection network modified special material preparation method | 界首市天路包装材料有限公司 | 2018-02-23 | — | — | CN | claimed |
| CN-104909399-B | A kind of ultrapure cerium oxygen compound colloidal sol | 安徽江南晶盛新材料有限公司 | 2016-08-17 | — | — | CN | claimed |
| CN-104909399-A | Ultra-pure cerium oxide sol | ANHUI JIANGNAN JINGSHENG NEW MATERIALS CO LTD | 2015-09-16 | — | — | CN | claimed |
| CN-101861342-B | High definition printing with waterborne inks on non-porous substrates | RHODIA | 2012-11-21 | — | — | CN | claimed |
| CN-101717536-B | Waste plastic, montmorillonoid and waste rubber composite and preparation method thereof | SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) | 2011-12-07 | — | — | CN | claimed |
| CN-101861342-A | High definition printing with waterborne inks on non-porous substrates | RHODIA | 2010-10-13 | — | — | CN | claimed |
| CN-101717536-A | Waste plastic, montmorillonoid and waste rubber composite and preparation method thereof | UNIV SOUTH CHINA TECH | 2010-06-02 | — | — | CN | claimed |
| CN-1137198-C | Nano composite polymer-montmorillonoid material and its prepn. | 中科纳米技术工程中心有限公司 | 2004-02-04 | — | — | CN | claimed |
| CN-1375516-A | Nano composite polymer-montmorillonoid material and its prepn. | CHINESE ACAD INST CHEMISTRY (CN) | 2002-10-23 | — | — | CN | claimed |
| US-4105694-A | Process for making trimethylamine acrylimide | POLAROID CORPORATION (US) | 1978-08-08 | — | — | US | claimed |
| CN-114601744-B | Delivery of surfactant soluble anti-dandruff agents | 宝洁公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-117551286-A | Water-absorbent resin and method for producing same | 台湾塑胶工业股份有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-117164948-A | Water-absorbent resin and method for producing same | 台湾塑胶工业股份有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-1137198-C | Nano composite polymer-montmorillonoid material and its prepn. | 中科纳米技术工程中心有限公司 | 2004-02-04 | — | — | CN | disclosed |
| CN-1375516-A | Nano composite polymer-montmorillonoid material and its prepn. | CHINESE ACAD INST CHEMISTRY (CN) | 2002-10-23 | — | — | CN | disclosed |
| CN-1243531-A | Aqueous dispersions of cationic polymers, their preparation and use | CIBA SPECIAL CHEMICALS TREATME (GB) | 2000-02-02 | — | — | CN | disclosed |
| US-4105694-A | Process for making trimethylamine acrylimide | POLAROID CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |