Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL176022 | 0.98 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Sulfuric Acid SCHEMBL27766767 | 0.89 | ZDHHC20 (0.36) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL15271262 | 0.89 | ZDHHC20 (0.46) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL27594490 | 0.86 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Lactic Acid SCHEMBL4910797 | 0.86 | TSHR (0.36) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| SCHEMBL9191360 | 0.85 | ZDHHC20 (0.37) | ZDHHC20ZDHHC2 | |
| L-Lactic Acid SCHEMBL4910791 | 0.85 | TSHR (0.35) | ZDHHC20ZDHHC2TSHR | |
| Hydrochloric Acid SCHEMBL2918034 | 0.83 | TSHR (0.39) | ZDHHC20ZDHHC2TSHRALDH1A1MAPK1 | |
| Bromide SCHEMBL8633399 | 0.82 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2TSHRALDH1A1THRA | |
| Bromide SCHEMBL4398412 | 0.82 | ZDHHC20 (0.51) | ZDHHC20ZDHHC2TSHRALDH1A1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070224145-A1 | Thickened Hair-Treatment Agent Containing Water Glass | WELLA AG (DE) | 2007-09-27 | — | — | US | claimed |
| CN-103773332-A | Drilling fluid and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2014-05-07 | — | — | CN | disclosed |