Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5487748 | 0.83 | ZDHHC20 (0.40) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL27901306 | 0.82 | ZDHHC20 (0.38) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL17076426 | 0.81 | ZDHHC20 (0.33) | ZDHHC20ZDHHC2 | |
| SCHEMBL176022 | 0.81 | ZDHHC20 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL15271262 | 0.80 | ZDHHC20 (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL27594490 | 0.78 | ZDHHC20 (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL3289299 | 0.77 | TSHR (0.42) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL3652807 | 0.74 | TSHR (0.44) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL10767222 | 0.74 | ZDHHC20 (0.39) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Bromide SCHEMBL8633399 | 0.74 | ZDHHC20 (0.51) | TSHRALDH1A1ZDHHC20ZDHHC2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111534294-A | Oil-containing sludge plugging agent and preparation method thereof | 中国石油天然气股份有限公司 | 2020-08-14 | — | — | CN | claimed |
| CN-111019062-A | Quick-hardening early-strength polycarboxylate superplasticizer and preparation method thereof | 重庆江通新型建材股份有限公司 | 2020-04-17 | — | — | CN | claimed |
| EP-1165878-B1 | SUBSTRATE COATINGS, METHODS FOR TREATING SUBSTRATES FOR INK JET PRINTING, AND ARTICLES PRODUCED THEREFROM | KIMBERLY CLARK CO (US) | 2008-05-28 | — | — | EP | claimed |
| US-6503977-B1 | Cationic polymer, fabric softener and water | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-01-07 | — | — | US | claimed |
| EP-1165878-A1 | SUBSTRATE COATINGS, METHODS FOR TREATING SUBSTRATES FOR INK JET PRINTING, AND ARTICLES PRODUCED THEREFROM | Kimberly-Clark Worldwide, Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056972-A1 | SUBSTRATE COATINGS, METHODS FOR TREATING SUBSTRATES FOR INK JET PRINTING, AND ARTICLES PRODUCED THEREFROM | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-09-28 | — | — | WO | claimed |
| CN-111534294-A | Oil-containing sludge plugging agent and preparation method thereof | 中国石油天然气股份有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111534294-A | Oil-containing sludge plugging agent and preparation method thereof | 中国石油天然气股份有限公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-111019062-A | Quick-hardening early-strength polycarboxylate superplasticizer and preparation method thereof | 重庆江通新型建材股份有限公司 | 2020-04-17 | — | — | CN | disclosed |
| CN-107530231-A | Low viscosity hair care compositions | 宝洁公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107530257-A | Delivery of surfactant soluble antidandruff agents | 宝洁公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107530239-A | Use the Hair Treatment Protocol of aerosol foam concentrated type conditioner | 宝洁公司 | 2018-01-02 | — | — | CN | disclosed |
| CN-107072934-A | Personal care compositions and methods of preparation | 宝洁公司 | 2017-08-18 | — | — | CN | disclosed |
| US-6503977-B1 | Cationic polymer, fabric softener and water | KIMBERLY-CLARK WORLDWIDE, INC. | 2003-01-07 | — | — | US | disclosed |
| EP-1240383-A2 | COATING FOR TEXTILES FOR INK JET PRINTING | Kimberly-Clark Worldwide, Inc. (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2002066731-A2 | COATING FOR TREATING SUBSTRATES FOR INK JET PRINTING | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020081421-A1 | Coating for treating substrates for ink jet printing including imbibing solution for enhanced image visualization and retention, method for treating said substrates, and articles produced threrefrom | KIMBERLY-CLARK WORLDWIDE, INC. | 2002-06-27 | — | — | US | disclosed |
| EP-1165878-A1 | SUBSTRATE COATINGS, METHODS FOR TREATING SUBSTRATES FOR INK JET PRINTING, AND ARTICLES PRODUCED THEREFROM | Kimberly-Clark Worldwide, Inc. (US) | 2002-01-02 | — | — | EP | disclosed |
| WO-2001032974-A2 | COATING FOR TEXTILES FOR INK JET PRINTING | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2001-05-10 | — | — | WO | disclosed |
| WO-2000056972-A1 | SUBSTRATE COATINGS, METHODS FOR TREATING SUBSTRATES FOR INK JET PRINTING, AND ARTICLES PRODUCED THEREFROM | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2000-09-28 | — | — | WO | disclosed |