SCHEMBL3289372

SCHEMBL3289372

Cc1cccc(C(=O)Cc2ccccc2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.58
RAB9A P51151 3/20 0.56
NPC1 O15118 2/20 0.56
SMN1; SMN2 Q16637 3/20 0.55
TDP1 Q9NUW8 2/20 0.55
ALDH1A1 P00352 1/20 0.55
LMNA P02545 1/20 0.55
HSP90AA1 P07900 1/20 0.55
HTT P42858 1/20 0.55
GPR52 Q9Y2T5 1/20 0.54
MEN1 O00255 1/20 0.54
FFAR1 O14842 1/20 0.54
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54
KMT2A Q03164 1/20 0.54
PARP1 P09874 1/20 0.52
MAPT P10636 1/20 0.51
POLB P06746 1/20 0.51
SRD5A2 P31213 2/20 0.50
PLAU P00749 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6359073 0.91 CTBP2 (0.54) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL165944 0.89 CTBP2 (0.57) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL11382971 0.89 RAB9A (0.57) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL16171153 0.88 MEN1 (0.52) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL3073424 0.85 NT5E (0.55) RAB9ANPC1SMN1; SMN2TDP1ALDH1A1
SCHEMBL3281032 0.85 KDM4E (0.58) RAB9ANPC1SMN1; SMN2ALDH1A1LMNA
SCHEMBL25760942 0.84 CTBP2 (0.49) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL3283011 0.83 KCNK3 (0.51) RAB9ANPC1SMN1; SMN2LMNAHTT
SCHEMBL6525838 0.83 L3MBTL1 (0.53) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1
SCHEMBL6525843 0.83 L3MBTL1 (0.53) L3MBTL1RAB9ANPC1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106547168-B Black matrix material composition and application 深圳市华星光电技术有限公司 2020-09-01 CN disclosed
EP-2468708-B1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts COGNIS IP MAN GMBH (DE) 2016-11-09 EP disclosed
EP-2468708-B1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts COGNIS IP MAN GMBH (DE) 2016-11-09 EP disclosed
EP-2018364-B1 THERAPEUTIC FLUOROETHYL UREAS ALLERGAN INC (US) 2013-08-21 EP disclosed
EP-2468708-A1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts Cognis IP Management GmbH (DE) 2012-06-27 EP disclosed
EP-2468708-A1 Catalytic decarboxylative cross-ketonisation of aryl- and alkylcarboxylic acids using iron catalysts Cognis IP Management GmbH (DE) 2012-06-27 EP disclosed
US-7709507-B2 Therapeutic fluoroethyl ureas ALLERGAN, INC. (US) 2010-05-04 US disclosed
EP-2018364-A1 THERAPEUTIC FLUOROETHYL UREAS Allergan, Inc. (US) 2009-01-28 EP disclosed
WO-2007137029-A1 THERAPEUTIC FLUOROETHYL UREAS ALLERGAN, INC. (US) 2007-11-29 WO disclosed
US-20070270498-A1 THERAPEUTIC FLUOROETHYL UREAS ALLERGAN, INC. 2007-11-22 US disclosed
US-4009022-A Selective antagonists for triazine herbicides ROHM AND HAAS COMPANY (US) 1977-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070270498-A1 THERAPEUTIC FLUOROETHYL UREAS SLC14A1, MAPT, UTS2R L3MBTL1 1009/4885RAB9A 684/4885NPC1 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.