Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTBP2 | P56545 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165944 | 0.91 | CTBP2 (0.57) | CTBP2POLBNPC1RAB9ATDP1 | |
| SCHEMBL3289372 | 0.91 | L3MBTL1 (0.58) | PARP1POLBCTNNB1WNT3ANPC1 | |
| SCHEMBL3280980 | 0.89 | KCNK3 (0.51) | CTBP2PARP1POLBNPC1RAB9A | |
| SCHEMBL3283011 | 0.89 | KCNK3 (0.51) | CTBP2PARP1CTNNB1WNT3ANPC1 | |
| SCHEMBL2477387 | 0.87 | NPC1 (0.57) | CTBP2POLBNPC1RAB9AL3MBTL1 | |
| SCHEMBL11382971 | 0.87 | RAB9A (0.57) | PARP1CTNNB1WNT3ANPC1RAB9A | |
| SCHEMBL25760942 | 0.86 | CTBP2 (0.49) | CTBP2POLBNPC1RAB9ATDP1 | |
| SCHEMBL9315993 | 0.86 | RAF1 (0.56) | CTBP2POLBHDAC6HPGDTDP1 | |
| SCHEMBL18214571 | 0.86 | KCNK3 (0.53) | CTBP2PARP1CTNNB1WNT3AHPGD | |
| SCHEMBL16171153 | 0.86 | MEN1 (0.52) | PARP1CTNNB1WNT3ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2016-05-19 | — | — | US | disclosed |
| US-9181162-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-8357210-B2 | Disazo acid dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2013-01-22 | — | — | US | disclosed |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2012-05-17 | — | — | US | disclosed |
| US-20110203058-A1 | Disazo Acid Dyes | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | CTBP2 782/4885PARP1 2679/4885POLB 3378/4885 |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | CTBP2 782/4885PARP1 2679/4885POLB 3378/4885 |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | CTBP2 782/4885PARP1 2679/4885POLB 3378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.