SCHEMBL3289947

SCHEMBL3289947

O=C(O)CC1C2C=CC(C2)C1C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 1/20 0.33
SLC6A12 P48065 3/20 0.32
SLC6A11 P48066 3/20 0.32
SLC6A13 Q9NSD5 3/20 0.32
KHK P50053 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3293814 0.84
SCHEMBL5848235 0.82 HSD11B1 (0.48) HSD11B1SMN1; SMN2L3MBTL1MAPK1SLC6A12
SCHEMBL6685953 0.78
SCHEMBL14532383 0.74
SCHEMBL13346663 0.73 POLB (0.45) HSD11B1SMN1; SMN2
SCHEMBL3297463 0.73 HSD11B1 (0.41) HSD11B1SMN1; SMN2L3MBTL1MAPK1SLC6A12
SCHEMBL13370655 0.73 HSD11B1 (0.41) HSD11B1SMN1; SMN2L3MBTL1MAPK1SLC6A12
SCHEMBL3289957 0.73 HSD11B1 (0.41) HSD11B1SMN1; SMN2L3MBTL1MAPK1SLC6A12
SCHEMBL1088471 0.73 NLRP3 (0.35)
SCHEMBL202551 0.72 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7727705-B2 High etch resistant underlayer compositions for multilayer lithographic processes FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. (US) 2010-06-01 US disclosed
WO-2008140846-A1 HIGH ETCH RESISTANT UNDERLAYER COMPOSITIONS FOR MULTILAYER LITHOGRAPHIC PROCESSES FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2008-11-20 WO disclosed
US-20080206667-A1 HIGH ETCH RESISTANT UNDERLAYER COMPOSITIONS FOR MULTILAYER LITHOGRAPHIC PROCESSES FUJIFILM ELECTRONIC MATERIALS, U.S.A., INC. 2008-08-28 US disclosed