⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19619081 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL659852 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL5050260 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL16705142 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL7139438 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL1480357 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL14619008 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL16704820 | 0.80 | USP2 (0.33) | — | |
| SCHEMBL202551 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL3289947 | 0.78 | HSD11B1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476788-A2 | FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME | Honeywell International Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| US-20030232276-A1 | Polymers derived from fluoroalkyl norbornenes, fluorinated crotonates, and/or fluorinated allyl alcohols; Diels Alder reaction of a fluorinated crotonate with cyclopentadiene to form said norbornene; photoresists; dielectrics, light guides | HONEYWELL INTERNATIONAL INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003073169-A2 | FLUORINATED MOLECULES AND METHODS OF MAKING AND USING SAME | HONEYWELL INTERNATIONAL INC. (US) | 2003-09-04 | — | — | WO | disclosed |