Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1353883 | 1.00 | DNM1 (0.45) | DNM1CA12CA1CA9TSHR | |
| Bromide SCHEMBL9877704 | 1.00 | DNM1 (0.45) | DNM1CA12CA1CA9TSHR | |
| Bromide SCHEMBL1353881 | 1.00 | DNM1 (0.45) | DNM1CA12CA1CA9TSHR | |
| Ethane SCHEMBL27638602 | 0.96 | DNM1 (0.43) | DNM1CA12CA1CA9TSHR | |
| Bromide SCHEMBL29048086 | 0.96 | DNM1 (0.43) | DNM1CA12CA1CA9TSHR | |
| Hexane SCHEMBL28009287 | 0.96 | DNM1 (0.50) | DNM1CA12CA1CA9TSHR | |
| Hexane SCHEMBL28564868 | 0.96 | DNM1 (0.50) | DNM1CA12CA1CA9TSHR | |
| Bromide SCHEMBL8369863 | 0.96 | DNM1 (0.43) | DNM1CA12CA1CA9TSHR | |
| SCHEMBL3904839 | 0.96 | TSHR (0.46) | DNM1CA12CA1CA9TSHR | |
| SCHEMBL27566038 | 0.96 | TSHR (0.46) | DNM1CA12CA1CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118874463-A | Load type Pt2Cluster catalyst and preparation method and application thereof | 北京结力能源科技有限公司 | 2024-11-01 | — | — | CN | claimed |
| CN-118561684-A | Synthesis method for preparing carbonyl chloride through cyano carburetion | 中南大学 | 2024-08-30 | — | — | CN | claimed |
| CN-118005953-A | High-viscoelasticity double-network carboxymethyl chitosan gel and preparation method and application thereof | 苏州浩微生物医疗科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-117964654-A | Synthesis method of arginate-ammonium phosphonate | 南京盛德创赢生物科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-116239453-A | Synthesis method of pentaerythritol triallyl ether | 浙江皇马科技股份有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-112500533-B | Preparation process of water reducing agent | 湖北天安新型建材股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-110452199-B | Preparation method of feloxicib | 山东鲁抗舍里乐药业有限公司 | 2021-03-30 | — | — | CN | claimed |
| CN-112500533-A | Preparation process of water reducing agent | 湖北天安新型建材股份有限公司 | 2021-03-16 | — | — | CN | claimed |
| CN-108774650-B | Fur retanning process for preventing leather from discoloring | 平湖宏远汽车座椅有限公司 | 2020-12-22 | — | — | CN | claimed |
| US-10179795-B2 | Synthesis of amine boranes and polyhedral boranes | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2019-01-15 | — | — | US | claimed |
| US-20020041856-A1 | Use of an organometallic compound to protect and/or strengthen a keratin material, and treatment process | JEANNE-ROSE VALERIE (FR) | 2002-04-11 | — | — | US | claimed |
| US-6350873-B2 | CHEMICAL INTERMEDIATE FOR STAVUDINE | CLARIANT LIFE SCIENCE MOLECULES (ITALY) S.P.A. (IT) | 2002-02-26 | — | — | US | claimed |
| US-20010039342-A1 | Process for preparing 5'-acetylstavudine | ARCHIMICA S.R.L. (IT) | 2001-11-08 | — | — | US | claimed |
| WO-2001077103-A1 | PROCESS FOR PREPARING 5'-ACETYLSTAVUDINE | CLARIANT LIFE SCIENCE MOLECULES (ITALIA) S.P.A. (IT) | 2001-10-18 | — | — | WO | claimed |
| US-5780195-A | POLYESTER RESIN CROSSLINKED WITH POLYFUNCTIONAL EPOXY RESIN IN PRESENCE OF CATALYST | REICHHOLD CHEMICALS, INC. (US) | 1998-07-14 | — | — | US | claimed |
| EP-0850436-A1 | TONER RESIN COMPOSITIONS | REICHHOLD CHEMICALS, INC. (US) | 1998-07-01 | — | — | EP | claimed |
| WO-1997049006-A1 | TONER RESIN COMPOSITIONS | REICHHOLD CHEMICALS, INC. (US) | 1997-12-24 | — | — | WO | claimed |
| US-5659035-A | Substituted phosphonic acids | ALBRIGHT & WILSON LIMITED (GB) | 1997-08-19 | — | — | US | claimed |
| US-5290958-A | Phase transfer catalytic process for preparing intermediates of atenolol, propranolol, and their derivatives | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 1994-03-01 | — | — | US | claimed |
| US-5082581-A | Aqueous magnetic fluid composition and process for producing thereof | NIPPON SEIKO KABUSHIKI KAISHA (JP) | 1992-01-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010039342-A1 | Process for preparing 5'-acetylstavudine | APRT, SAMHD1, DIMT1 | DNM1 1225/4885CA12 4358/4885CA1 4372/4885 |
| US-20020041856-A1 | Use of an organometallic compound to protect and/or strengthen a keratin material, and treatment process | KRT18, VIM, CDH1 | DNM1 3784/4885CA12 170/4885CA1 132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.