SCHEMBL3290399

SCHEMBL3290399

CCCCCCCCCCCCCCCCCCC(O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)P(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FDPS P14324 4/20 0.53
LAP3 P28838 2/20 0.50
PTPN1 P18031 1/20 0.46
S1PR2 O95136 5/20 0.46
S1PR1 P21453 5/20 0.46
S1PR3 Q99500 5/20 0.46
S1PR4 O95977 4/20 0.46
SMPD1 P17405 3/20 0.44
SPHK1 Q9NYA1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11218189 0.80 SPHK1 (0.56) FDPSSPHK1
SCHEMBL9240010 0.79 LAP3 (0.59) FDPSLAP3PTPN1S1PR2S1PR1
SCHEMBL2385582 0.76 SPHK1 (0.62) SPHK1
SCHEMBL3344513 0.76 SPHK1 (0.62) SPHK1
SCHEMBL13825654 0.76 SPHK1 (0.62) SPHK1
SCHEMBL10607850 0.76 SPHK1 (0.62) SPHK1
SCHEMBL136612 0.76 SPHK1 (0.62) SPHK1
SCHEMBL7756046 0.76 SPHK1 (0.62) SPHK1
SCHEMBL10605211 0.76 SPHK1 (0.62) SPHK1
SCHEMBL27963355 0.76 SPHK1 (0.62) SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172631-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. (DE) 2012-07-05 US disclosed
US-8076520-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2011-12-13 US disclosed
US-20100280282-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2010-11-04 US disclosed
US-7709464-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. (DE) 2010-05-04 US disclosed
US-20090035358-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2009-02-05 US disclosed
US-7351428-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2008-04-01 US disclosed
US-6413543-B1 DRUG DELIVERY MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2002-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100280282-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG FDPS 1510/4885LAP3 1299/4885PTPN1 2213/4885
US-20120172631-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG FDPS 1510/4885LAP3 1299/4885PTPN1 2213/4885
US-20090035358-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG FDPS 1510/4885LAP3 1299/4885PTPN1 2213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.