Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 2/20 | 0.59 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.54 |
| ▸ | FDPS | P14324 | 4/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | GMNN | O75496 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THPO | P40225 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CETP | P11597 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554032 | 0.81 | LAP3 (0.63) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL3290399 | 0.79 | FDPS (0.53) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| Phosphoric Acid SCHEMBL16245452 | 0.78 | CYP2D6 (0.63) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL29773364 | 0.77 | SPHK1 (0.65) | LAP3SPHK1CYP2D6GMNNLMNA | |
| SCHEMBL9557240 | 0.76 | FDPS (0.59) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| Dihydrospingosine SCHEMBL7594434 | 0.75 | CYP2D6 (0.82) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5270800 | 0.75 | SPHK1 (0.69) | LAP3SPHK1CYP2D6GMNNLMNA | |
| SCHEMBL5691588 | 0.75 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL9307335 | 0.75 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL5691911 | 0.75 | LAP3 (1.00) | LAP3S1PR2S1PR1S1PR3S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995021848-A1 | SPHINGOID BASES AND METHODS FOR THEIR PREPARATION AND USE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE (US) | 1995-08-17 | — | — | WO | disclosed |
| US-5430169-A | Method for preparation of sphingoid bases | THE UNITED STATES OF AMERICA REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-07-04 | — | — | US | disclosed |