Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 8/20 | 0.56 |
| ▸ | KLK1 | P06870 | 8/20 | 0.56 |
| ▸ | KLK6 | Q92876 | 8/20 | 0.56 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 6/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13593307 | 0.85 | P2RX1 (0.66) | KLKB1ALOX15NR1H4 | |
| SCHEMBL13593313 | 0.85 | ALOX15 (0.54) | PLGKLK1KLK6KLKB1ALOX15 | |
| SCHEMBL13293974 | 0.84 | PLG (0.61) | PLGKLK1KLK6KLKB1NR1H4 | |
| SCHEMBL14289050 | 0.82 | PLAU (0.58) | PLGKLK1KLK6KLKB1ALOX15 | |
| SCHEMBL6381563 | 0.82 | ALOX15 (0.70) | PLGALOX15NR1H4 | |
| SCHEMBL13593311 | 0.80 | PLG (0.67) | PLGKLK1KLK6ALOX15NR1H4 | |
| SCHEMBL5656623 | 0.78 | ALOX15 (0.72) | PLGALOX15NR1H4 | |
| SCHEMBL28748746 | 0.78 | FFAR1 (0.54) | — | |
| SCHEMBL5657536 | 0.78 | ALOX15 (0.57) | PLGKLK1KLK6KLKB1ALOX15 | |
| SCHEMBL3290565 | 0.77 | MAPK1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727558-B2 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070141022-A1 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECHNOLOGIES, INC. | 2007-06-21 | — | — | US | disclosed |
| US-7208483-B2 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-20030232085-A1 | Polymeric delivery agents and delivery agent compounds | EMISPHERE TECHNOLOGIES, INC. | 2003-12-18 | — | — | US | disclosed |
| US-6627228-B1 | Polymeric delivery agents and delivery agents compounds | EMISPHERE TECHNOLOGIES, INC. | 2003-09-30 | — | — | US | disclosed |
| EP-1146860-A4 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECH INC (US) | 2002-07-03 | — | — | EP | disclosed |
| EP-1146860-A2 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | Emisphere Technologies, Inc. (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000040203-A2 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | EMISPHERE TECHNOLOGIES, INC. (US) | 2000-07-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141022-A1 | POLYMERIC DELIVERY AGENTS AND DELIVERY AGENT COMPOUNDS | LPXN, PGF, TTPA | PLG 51/4885KLK1 3635/4885KLK6 1997/4885 |
| US-20030232085-A1 | Polymeric delivery agents and delivery agent compounds | LPXN, PGF, TTPA | PLG 51/4885KLK1 3635/4885KLK6 1997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.