SCHEMBL3290529

SCHEMBL3290529

CCC[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LGALS1 P09382 2/20 0.48
LGALS3 P17931 2/20 0.48
LGALS9 O00182 1/20 0.48
LGALS8 O00214 1/20 0.48
PYGB P11216 3/20 0.47
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.41
OGA O60502 1/20 0.40
MAPT P10636 1/20 0.40
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26987277 1.00 LGALS1 (0.48) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL757840 1.00 LGALS1 (0.48) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL3292990 1.00 LGALS1 (0.48) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL388109 0.98 LGALS1 (0.45) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL17087922 0.98 LGALS1 (0.45) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL23848882 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL8347365 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL12993503 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL14028866 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB
SCHEMBL16644800 0.87 GBA1 (0.46) LGALS1LGALS3LGALS9LGALS8PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049300-B2 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL (FR) 2006-05-23 US claimed
US-20040048785-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans SOCIETE L'OREAL S.A. (FR) 2004-03-11 US claimed
EP-1345919-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2003-09-24 EP claimed
WO-2002051828-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2002-07-04 WO claimed
EP-1345919-B1 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF OREAL (FR) 2013-05-22 EP disclosed
US-7732414-B2 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL S.A. (FR) 2010-06-08 US disclosed
US-20060223763-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL S.A. (FR) 2006-10-05 US disclosed
US-7049300-B2 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans L'OREAL (FR) 2006-05-23 US disclosed
US-20040048785-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans SOCIETE L'OREAL S.A. (FR) 2004-03-11 US disclosed
EP-1345919-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2003-09-24 EP disclosed
WO-2002051828-A2 NOVEL C-GLYCOSIDE DERIVATIVES AND USE THEREOF L'OREAL (FR) 2002-07-04 WO disclosed
US-5885968-A FOR HYPOLIPIDEMIC MEDICINES RIJKSUNIVERSITEIT TE LEIDEN (NL) 1999-03-23 US disclosed
EP-0655070-B1 TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE UNIV LEIDEN (NL) 1998-07-22 EP disclosed
EP-0655070-A1 TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE RIJKSUNIVERSITEIT LEIDEN (NL) 1995-05-31 EP disclosed
WO-1994004545-A1 TRIANTENNARY CLUSTER GLYCOSIDES, THEIR PREPARATION AND USE RIJKSUNIVERSITEIT LEIDEN (NL) 1994-03-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223763-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans CSGALNACT1, FUT6, AREG LGALS1 182/4885LGALS3 124/4885LGALS9 239/4885
US-20040048785-A1 C-glycoside compounds for stimulating the synthesis of glycosaminoglycans CSGALNACT1, FUT6, AREG LGALS1 182/4885LGALS3 124/4885LGALS9 239/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.